Recent Advances in the Synthesis of Sulfonamides Intermediates
Abstract: Sulfonamides are one of the most important synthons in drug synthesis, which can increase the water solubility of drugs and regulate their metabolism in vivo. According to statistics, nearly 30% of sulfur-containing drugs on the market contain sulfonamide groups, including omeprazole, hydrochlorothiazide, and other best-selling drugs. Synthesis of sulfonamide is therefore a very important part of new drug development and active pharmaceutical ingredient manufacturing. In this review, we will focus on the recent 5-year advances in the field of synthetic research and structural modification of sulfonamide-containing drugs and their intermediates. The synthesis strategies, including S−N construction, C−N cross-coupling, N−H functionalization, and C−H sulfonamidation, are discussed, hoping to provide new ideas for the researchers to prepare sulfonamides in a green and efficient way.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Recent Advances in the Synthesis of Sulfonamides Intermediates ; volume:06 ; number:04 ; year:2024 ; pages:e355-e381
Pharmaceutical fronts ; 06, Heft 04 (2024), e355-e381
- Beteiligte Personen und Organisationen
-
Liu, Wei
Chen, Jianli
Su, Weike
- DOI
-
10.1055/s-0044-1796646
- URN
-
urn:nbn:de:101:1-2502131104477.534176402535
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:35 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Liu, Wei
- Chen, Jianli
- Su, Weike
Ähnliche Objekte (12)
Journal of Translational Medicine advances in Translational Genomics and Genetics Era
Fine properties of stochastic evolution equations and their applications
Aristotle on Prohairesis
Memoiren als Spiegel der Zeitgeschichte : Die Beziehungen zwischen der Republik China und dem Dritten Reich
Magnetic Fe3O4 based layered double hydroxides (LDHs) nanocomposites (Fe3O4/LDHs): recent review of progress in synthesis, properties and applications
The cause, features and effects of current policy mix of opposing fiscal and monetary policies
Some latest achievements in immunology research
Do Institutional Investors Drive Financialization of Real Sectors?
Recent Development of Self‐Supported Alkaline Hydrogen Evolution Reaction Electrocatalysts for Industrial Electrolyzer
Multifactor market indexes
Double ligation-assisted endoscopic submucosal resection for rectal neuroendocrine tumors
Cross-talk between cd1d-restricted nkt cells and γδ cells in t regulatory cell response
Journal of Translational Medicine advances in Translational Genomics and Genetics Era
Fine properties of stochastic evolution equations and their applications
Aristotle on Prohairesis
Memoiren als Spiegel der Zeitgeschichte : Die Beziehungen zwischen der Republik China und dem Dritten Reich
Magnetic Fe3O4 based layered double hydroxides (LDHs) nanocomposites (Fe3O4/LDHs): recent review of progress in synthesis, properties and applications
The cause, features and effects of current policy mix of opposing fiscal and monetary policies
Some latest achievements in immunology research
Do Institutional Investors Drive Financialization of Real Sectors?
Recent Development of Self‐Supported Alkaline Hydrogen Evolution Reaction Electrocatalysts for Industrial Electrolyzer
Multifactor market indexes
Double ligation-assisted endoscopic submucosal resection for rectal neuroendocrine tumors
Cross-talk between cd1d-restricted nkt cells and γδ cells in t regulatory cell response
Journal of Translational Medicine advances in Translational Genomics and Genetics Era
Fine properties of stochastic evolution equations and their applications
Aristotle on Prohairesis
Memoiren als Spiegel der Zeitgeschichte : Die Beziehungen zwischen der Republik China und dem Dritten Reich
Magnetic Fe3O4 based layered double hydroxides (LDHs) nanocomposites (Fe3O4/LDHs): recent review of progress in synthesis, properties and applications
The cause, features and effects of current policy mix of opposing fiscal and monetary policies
Some latest achievements in immunology research
Do Institutional Investors Drive Financialization of Real Sectors?
Recent Development of Self‐Supported Alkaline Hydrogen Evolution Reaction Electrocatalysts for Industrial Electrolyzer
Multifactor market indexes
Double ligation-assisted endoscopic submucosal resection for rectal neuroendocrine tumors