Synthesis of (6,5,5) Ring‐Fused Tricyclic Triazoles by Copper‐Promoted Double Cyclization

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Abstract: Ring‐fused 1,2,3‐triazoles are important biologically active compounds and synthetic intermediates. Known methods for their synthesis are limited mostly to triazoles fused to six‐membered or larger rings. Herein we disclose a synthetic approach to triazoles fused to five‐membered rings based on copper (I)‐promoted double cyclization consisting of azide‐alkyne cycloaddition, followed by cross coupling to aryl iodides.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Synthesis of (6,5,5) Ring‐Fused Tricyclic Triazoles by Copper‐Promoted Double Cyclization ; day:25 ; month:10 ; year:2024 ; extent:5
European journal of organic chemistry ; (25.10.2024) (gesamt 5)

Creator: Pošta, Martin
Dmitrieva, Margarita
Volpe, Chiara
Matoušek, Václav
Klepetářová, Blanka
Beier, Petr

DOI: 10.1002/ejoc.202400736

URN: urn:nbn:de:101:1-2410261428231.489653269176

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:31 AM CEST

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Pošta, Martin
Dmitrieva, Margarita
Volpe, Chiara
Matoušek, Václav
Klepetářová, Blanka
Beier, Petr

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Synthesis of (6,5,5) Ring‐Fused Tricyclic Triazoles by Copper‐Promoted Double Cyclization

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Other Objects (12)

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