PAKC: A novel Panel of HLA class I Antigen presentation machinery Knockout Cells from the same genetic origin
Abstract: A single model system for integrative studies on multiple facets of antigen presentation is lacking. PAKC is a novel panel of ten cell lines knocked out for individual components of the HLA class I antigen presentation pathway. PAKC will accelerate HLA‐I research in the fields of oncology, infectiology, and autoimmunity
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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European journal of immunology. - 51, 3 (2021) , 734-737, ISSN: 1521-4141
- Event
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Veröffentlichung
- (where)
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Freiburg
- (who)
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Universität
- (when)
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2021
- Creator
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Waard, Antonius A.
Verkerk, Tamara
Jongsma, Marlieke L. M.
Hoefakker, Kelly
Sethumadhavan, Sunesh
Gerke, Carolin
Bliss, Sophie
Kong, Xiangrui
Janssen, George M.C
Ru, Arnoud H.
Claas, Frans H.
Mulder, Arend
Tampé, Robert
Veelen, Peter A.
Halenius, Anne
Spaapen, Robbert M.
- DOI
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10.1002/eji.202048599
- URN
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urn:nbn:de:bsz:25-freidok-1749348
- Rights
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:57 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Waard, Antonius A.
- Verkerk, Tamara
- Jongsma, Marlieke L. M.
- Hoefakker, Kelly
- Sethumadhavan, Sunesh
- Gerke, Carolin
- Bliss, Sophie
- Kong, Xiangrui
- Janssen, George M.C
- Ru, Arnoud H.
- Claas, Frans H.
- Mulder, Arend
- Tampé, Robert
- Veelen, Peter A.
- Halenius, Anne
- Spaapen, Robbert M.
- Universität
Time of origin
- 2021
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PAKC: a novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin
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PAKC: a novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin
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Time‐Resolved Mn 2+ −NO and NO−NO Distance Measurements Reveal That Catalytic Asymmetry Regulates Alternating Access in an ABC Transporter **
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Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9)
The epidermal growth factor receptor is a relevant host factor in the early stages of the Zika virus life cycle in vitro
Mechanistic insights into ribosome recycling and quality control in mRNA translation
Mechanistic and structural insights into the quality control of the MHC I antigen processing pathway
Mechanistic and structural studies of the MHC I peptide loading complex
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PAKC: a novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin
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Time‐Resolved Mn 2+ −NO and NO−NO Distance Measurements Reveal That Catalytic Asymmetry Regulates Alternating Access in an ABC Transporter **
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