Commercial high-throughput sequencing and its applications in DNA analysis

Abstract: DNA sequences can be used for the analysis of genetic variation and gene function. The high-throughput sequencing techniques that have been developed over the past three years can read as many as one billion bases per run, and are far less expensive than the traditional Sanger sequencing method. Therefore, the high-throughput sequencing has been applied extensively to genomic analyses, such as screening for mutations, construction of genomic methylation maps, and the study of DNA-protein interactions. Although they have only been available for a short period, high-throughput sequencing techniques are profoundly affecting many of the life sciences, and are opening out new potential avenues of research. With the highly-developed commercial high-throughput sequencing platforms, each laboratory has the opportunity to explore this research field. Therefore, in this paper, we have focused on commercially-popular high-throughput sequencing techniques and the ways in which they have been applied over the past three years.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Commercial high-throughput sequencing and its applications in DNA analysis ; volume:64 ; number:1 ; year:2009 ; pages:20-26 ; extent:7
Biologia ; 64, Heft 1 (2009), 20-26 (gesamt 7)

Urheber
Peng, Hai
Zhang, Jing

DOI
10.2478/s11756-009-0028-4
URN
urn:nbn:de:101:1-2409221615328.014705543461
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:29 MESZ

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Beteiligte

  • Peng, Hai
  • Zhang, Jing

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