Synthesis and anti-proliferative activity of pyridine O -galactosides and 4-fluorobenzoyl analogues
Abstract: Pyridine O-galactosides 3, 4, and 2-(4′-fluorobenzoyloxy) pyridine derivatives 5 were prepared by simple nucleophilic substitution reactions. These nucleosides were studied as anti-proliferating agents of human promyelotic leukemia (HL-60) cells. Compound 5a shows the highest anti-proliferative activity (77% at 100 μm) among the synthesized compounds.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Synthesis and anti-proliferative activity of pyridine O -galactosides and 4-fluorobenzoyl analogues ; volume:21 ; number:5 ; year:2015 ; pages:285-290 ; extent:6
Heterocyclic communications ; 21, Heft 5 (2015), 285-290 (gesamt 6)
- Urheber
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Alneyadi, Shaikha S.
Shehadi, Ihsan A.
Abdou, Ibrahim M.
- DOI
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10.1515/hc-2015-0125
- URN
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urn:nbn:de:101:1-2501130622596.981752213462
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:33 MESZ
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Beteiligte
- Alneyadi, Shaikha S.
- Shehadi, Ihsan A.
- Abdou, Ibrahim M.
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