Innovation of Expanded‐Bed Adsorption by Integrating Simulated Moving‐Bed Technology

Abstract: Bio‐based industries need efficient downstream solutions to process complex streams. This was addressed through a technology integration approach, where expanded‐bed adsorption (EBA) is integrated with simulated moving‐bed (SMB) technology. Current work involved adaptation of an SMB apparatus and control principle to implement expanded‐bed level control. As an outcome, EBA‐SMB technology was successfully applied for purification of γ‐aminobutyric acid (GABA). This resulted in two‐fold increase in productivity and a GABA purity ≥ 92 % in one step from unclarified fermentation broth, compared to ≥ 93 % purity in case of clarified broth and packed‐bed SMB. These results proved that EBA‐SMB technology is able to enhance process efficiency and economics of bioprocesses.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Innovation of Expanded‐Bed Adsorption by Integrating Simulated Moving‐Bed Technology ; volume:41 ; number:12 ; year:2018 ; pages:2393-2401 ; extent:9
Chemical engineering & technology ; 41, Heft 12 (2018), 2393-2401 (gesamt 9)

Urheber
Pathapati, Trinath
Rutze, Dennis N.
de Wit, Pieter
den Boer, Piet
Zaalberg, Menne

DOI
10.1002/ceat.201800293
URN
urn:nbn:de:101:1-2022090109482923748120
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:28 MESZ

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Beteiligte

  • Pathapati, Trinath
  • Rutze, Dennis N.
  • de Wit, Pieter
  • den Boer, Piet
  • Zaalberg, Menne

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