Natural probiotics improve heritable sterility
Disrupting the small RNA pathway and chromatin‐modifying enzymes in C. elegans often leads to a mortal germline (Mrt) phenotype, characterized by progressive sterility observed over multiple generations at elevated temperature. This phenotype arises from the inheritance of aberrant epigenetic memory across generations. In this issue of EMBO Reports, Frézal and colleagues reported that, while in standard laboratory environment C. elegans wild isolates exhibit the Mrt phenotype, sterility does not occur when the worms are exposed to naturally associated bacteria and microsporidia. Excitingly, diet‐induced epigenetic memory may persist for multiple generations. This suggests intriguing diet–gene interactions in modulating nongenetic inheritance, potentially shaping the evolutionary trajectory of the animals.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Natural probiotics improve heritable sterility ; day:20 ; month:11 ; year:2023 ; extent:3
EMBO reports / European Molecular Biology Organization ; (20.11.2023) (gesamt 3)
- Creator
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Ewe, Chee Kiang
Rechavi, Oded
- DOI
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10.15252/embr.202358318
- URN
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urn:nbn:de:101:1-2023112114051349434090
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:28 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Ewe, Chee Kiang
- Rechavi, Oded
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