Emergence of Elastic Properties in a Minimalist Resilin‐Derived Heptapeptide upon Bromination

Abstract: Bromination is herein exploited to promote the emergence of elastic behavior in a short peptide—SDSYGAP—derived from resilin, a rubber‐like protein exerting its role in the jumping and flight systems of insects. Elastic and resilient hydrogels are obtained, which also show self‐healing behavior, thanks to the promoted non‐covalent interactions that limit deformations and contribute to the structural recovery of the peptide‐based hydrogel. In particular, halogen bonds may stabilize the β‐sheet organization working as non‐covalent cross‐links between nearby peptide strands. Importantly, the unmodified peptide (i.e., wild type) does not show such properties. Thus, SDSY (3,5‐Br) GAP is a novel minimalist peptide elastomer.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Emergence of Elastic Properties in a Minimalist Resilin‐Derived Heptapeptide upon Bromination ; day:20 ; month:06 ; year:2022 ; extent:10 ; Small ; (20.06.2022) (gesamt 10)

Contributors, Places and Time

• Creator: Pizzi, Andrea ; Sori, Lorenzo ; Pigliacelli, Claudia ; Gautieri, Alfonso ; Andolina, Clara ; Bergamaschi, Greta ; Gori, Alessandro ; Panine, Pierre ; Grande, Antonio Mattia ; Linder, Markus B. ; Baldelli Bombelli, Francesca ; Soncini, Monica ; Metrangolo, Pierangelo

Further information

• DOI: 10.1002/smll.202200807
• URN: urn:nbn:de:101:1-2022062015210661614741
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:23 AM CEST