Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2045-2322

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells ; volume:8 ; number:1 ; day:3 ; month:8 ; year:2018 ; pages:1-10 ; date:12.2018
Scientific reports ; 8, Heft 1 (3.8.2018), 1-10, 12.2018

Classification: Medizin, Gesundheit

Creator: Trifunov, Selena

Contributor: Pyle, Angela
Valentino, Maria Lucia
Liguori, Rocco
Yu-Wai-Man, Patrick
Burté, Florence
Duff , Jennifer
Kleinle, Stephanie
Diebold, Isabel
Rugolo, Michela
Horvath, Rita
Carelli, Valerio
SpringerLink (Online service)

DOI: 10.1038/s41598-018-30143-z

URN: urn:nbn:de:101:1-2018100121364769913273

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:28 AM CEST

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Associated

Trifunov, Selena
Pyle, Angela
Valentino, Maria Lucia
Liguori, Rocco
Yu-Wai-Man, Patrick
Burté, Florence
Duff , Jennifer
Kleinle, Stephanie
Diebold, Isabel
Rugolo, Michela
Horvath, Rita
Carelli, Valerio
SpringerLink (Online service)

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POLG1 p.R722H mutation associated with multiple mtDNA deletions and a neurological phenotype

Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness

Deletions in the 17q chromosomal region and their influence on the clonal cytogenetic evolution of recurrent meningiomas

Increased levels of large scale deletions of mtDNA of skin fibroblasts result in increased collagen degradation in dermal skin equivalents

Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures

The dynamics of milk droplet–droplet collisions

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Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics

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ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

POLG1 p.R722H mutation associated with multiple mtDNA deletions and a neurological phenotype

Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness

Deletions in the 17q chromosomal region and their influence on the clonal cytogenetic evolution of recurrent meningiomas

Increased levels of large scale deletions of mtDNA of skin fibroblasts result in increased collagen degradation in dermal skin equivalents

Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures

The dynamics of milk droplet–droplet collisions

Droplet separation

Genomic insights from whole genome sequencing of four clonal outbreak Campylobacter jejuni assessed within the global C. jejuni population

Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics

Occurrence of gastrointestinal nematodes in lambs in Norway, as assessed by copromicroscopy and droplet digital polymerase chain reaction

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Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells

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Other Objects (12)

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

POLG1 p.R722H mutation associated with multiple mtDNA deletions and a neurological phenotype

Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness

Deletions in the 17q chromosomal region and their influence on the clonal cytogenetic evolution of recurrent meningiomas

Increased levels of large scale deletions of mtDNA of skin fibroblasts result in increased collagen degradation in dermal skin equivalents

Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures

The dynamics of milk droplet–droplet collisions

Droplet separation

Genomic insights from whole genome sequencing of four clonal outbreak Campylobacter jejuni assessed within the global C. jejuni population

Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics

Occurrence of gastrointestinal nematodes in lambs in Norway, as assessed by copromicroscopy and droplet digital polymerase chain reaction

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

POLG1 p.R722H mutation associated with multiple mtDNA deletions and a neurological phenotype

Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness

Deletions in the 17q chromosomal region and their influence on the clonal cytogenetic evolution of recurrent meningiomas

Increased levels of large scale deletions of mtDNA of skin fibroblasts result in increased collagen degradation in dermal skin equivalents

Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures

The dynamics of milk droplet–droplet collisions

Droplet separation

Genomic insights from whole genome sequencing of four clonal outbreak Campylobacter jejuni assessed within the global C. jejuni population

Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics

Occurrence of gastrointestinal nematodes in lambs in Norway, as assessed by copromicroscopy and droplet digital polymerase chain reaction

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

POLG1 p.R722H mutation associated with multiple mtDNA deletions and a neurological phenotype

Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness

Deletions in the 17q chromosomal region and their influence on the clonal cytogenetic evolution of recurrent meningiomas

Increased levels of large scale deletions of mtDNA of skin fibroblasts result in increased collagen degradation in dermal skin equivalents

Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures

The dynamics of milk droplet–droplet collisions

Droplet separation

Genomic insights from whole genome sequencing of four clonal outbreak Campylobacter jejuni assessed within the global C. jejuni population

Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics

Occurrence of gastrointestinal nematodes in lambs in Norway, as assessed by copromicroscopy and droplet digital polymerase chain reaction

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