Four phosphates at one blow: access to pentaphosphorylated magic spot nucleotides and their analysis by capillary electrophoresis
Abstract: The complex phosphorylation pattern of natural and modified pentaphosphorylated magic spot nucleotides is generated in a highly efficient way. A cyclic pyrophosphoryl phosphoramidite (cPyPA) reagent is used to introduce four phosphates on nucleosides regioselectively in a one-flask key transformation. The obtained magic spot nucleotides are used to develop a capillary electrophoresis UV detection method, enabling nucleotide assignment in complex bacterial extracts
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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The journal of organic chemistry. - 85, 22 (2020) , 14496–14506, ISSN: 1520-6904
- Event
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Veröffentlichung
- (where)
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Freiburg
- (who)
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Universität
- (when)
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2020
- DOI
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10.1021/acs.joc.0c00841
- URN
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urn:nbn:de:bsz:25-freidok-1665462
- Rights
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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25.03.2025, 1:47 PM CET
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
Time of origin
- 2020
Other Objects (12)
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Untersuchungen zur intrazellulären Freisetzung von Nucleosidphosphaten
Investigations on the synthesis and degradation of polyphosphate in vitro and its correlation to magic spot nucleotides
Photocages, photocaged nucleotides and subcellular delivery
Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues
Capillary zone electrophoresis
Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
Instrumentation for capillary electrophoresis and microchip electrophoresis
Capillary electrophoresis : principles and practice
Capillary electrophoresis : methods and potentials
Capillary electrophoresis-, liquid chromatography-mass spectrometry
Analysis of pharmaceuticals by capillary electrophoresis
Analysis of carbohydrates by capillary electrophoresis
Untersuchungen zur intrazellulären Freisetzung von Nucleosidphosphaten
Investigations on the synthesis and degradation of polyphosphate in vitro and its correlation to magic spot nucleotides
Photocages, photocaged nucleotides and subcellular delivery
Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues
Capillary zone electrophoresis
Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
Instrumentation for capillary electrophoresis and microchip electrophoresis
Capillary electrophoresis : principles and practice
Capillary electrophoresis : methods and potentials
Capillary electrophoresis-, liquid chromatography-mass spectrometry
Analysis of pharmaceuticals by capillary electrophoresis