Generating Vectors for the Lattice Structures of Tubular and Conical Viral Capsids

Abstract: Retrovirus capsid is a fullerene-like lattice consisting of capsid protein hexamers and pentamers. Mathematical models for the lattice structure help understand the underlying biological mechanisms in the formation of viral capsids. It is known that viral capsids could be categorized into three major types: icosahedron, tube, and cone. While the model for icosahedral capsids is established and well-received, models for tubular and conical capsids need further investigation. This paper proposes new models for the tubular and conical capsids based on an extension of the Capser-Klug quasi-equivalence theory. In particular, two and three generating vectors are used to characterize respectively the lattice structures of tubular and conical capsids. Comparison with published HIV-1 data demonstrates a good agreement of our modeling results with experimental data.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Generating Vectors for the Lattice Structures of Tubular and Conical Viral Capsids ; volume:2 ; number:1 ; year:2014 ; pages:128-140 ; extent:13
Computational and mathematical biophysics ; 2, Heft 1 (2014), 128-140 (gesamt 13)

Urheber
Sadre-Marandi, Farrah
Liu, Jiangguo
Tavener, Simon
Chen, Chaoping

DOI
10.2478/mlbmb-2014-0009
URN
urn:nbn:de:101:1-2410261646580.593013068002
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:35 MESZ

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Beteiligte

  • Sadre-Marandi, Farrah
  • Liu, Jiangguo
  • Tavener, Simon
  • Chen, Chaoping

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