Multifrequency bioimpedance device based on the Analog Discovery 2: performance and characterization

Abstract: Bioimpedance spectroscopy can be used to investigate the composition and monitor the human body, organs, tissues, or cell cultures by measuring the voltage developed by the injection of small alternating currents at different frequencies. These currents are injected sequentially through a frequency sweep and a with a Howland current source or one of its modifications. However, the frequency sweep is not time efficient and introduces problems with data coherence in the case of bioinstability. On the other hand, the Howland current source requires high precision matching between its components. In this contribution we developed a custom-made device for bioimpedance measurements based on a multisine current waveform and on a negative-feedback topology for the current source. Measurements on passive elements showed that the device had less than 1Ω and 0.05∘ uncertainty in the frequency range between 500 Hz and 200 kHz for impedance between 1 kΩ and 10 kΩ. The measurements were affected by an inductive artifact connected with the limited common-mode rejection at high frequencies. Nevertheless, we could characterize the artifacts through a fitting procedure to recover the expected value of the targeted impedance.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Multifrequency bioimpedance device based on the Analog Discovery 2: performance and characterization ; volume:9 ; number:1 ; year:2023 ; pages:536-539 ; extent:4
Current directions in biomedical engineering ; 9, Heft 1 (2023), 536-539 (gesamt 4)

Creator
Battistel, Alberto
Craamer Lizarraga, Hegoa
Termenon, Maite
Möller, Knut

DOI
10.1515/cdbme-2023-1134
URN
urn:nbn:de:101:1-2023092214222428894752
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:57 AM CEST

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