Stereoselective Synthetic Strategies to (−)‐Cannabidiol

Abstract: (−)‐Cannabidiol (CBD) is a non‐psychoactive compound that has already found many medical applications, from the treatment of epilepsy to other neurological disorders. (−)‐CBD is usually extracted from Cannabis Sativa, but unfortunately, its isolation among many other structurally related cannabinoids can be challenging. This, along with the increased demand for (−)‐CBD, prompted chemists to come up with synthetic strategies that could afford this cannabinoid in good yield and high enantiopurity. Herein, we aim to review the fundamental strategies employed in the stereoselective synthesis of (−)‐cannabidiol, spanning from classic approaches to automated ones, highlighting the challenges encountered in the total synthesis of this cannabinoid.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Stereoselective Synthetic Strategies to (−)‐Cannabidiol ; volume:7 ; number:28 ; year:2022 ; extent:8
ChemistrySelect ; 7, Heft 28 (2022) (gesamt 8)

Urheber
Maiocchi, Alice
Barbieri, Jacopo
Fasano, Valerio
Passarella, Daniele

DOI
10.1002/slct.202202400
URN
urn:nbn:de:101:1-2022072615121917970106
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:36 MESZ

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Beteiligte

  • Maiocchi, Alice
  • Barbieri, Jacopo
  • Fasano, Valerio
  • Passarella, Daniele

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