Recovery and Seasonal Variation of Cinnamtannin B‐1 from Laurel (Laurus nobilis L.) Pruning Wood Wastes

Abstract: Cinnamtannin B‐1 (C‐B1) is a commercially‐available trimeric A‐type procyanidin with remarkable cellular actions mainly derived from its high radical scavenging activity. C‐B1 is the main phenolic compound of laurel wood, which has previously been isolated by a combination of conventional chromatographic techniques. The first aim of this work was to find laurel trees containing as much C‐B1 as possible, and learn about the influence of variables, such as gender and harvest time, on the production of C‐B1 by the tree. It was found that all studied trees tend to give higher C‐B1 percentages in the May‐July period, from 6 % to 18 %, and lower ones around March (spring) and November (fall), from 1 % to 8 %. In a general way, it also seems that the female trees tend to produce a bit more C‐B1 (from 2.8 % to 17.3 %) than male ones (from 1.7 % to 13.4 %). In addition, eight minor phenolic compounds [(−)‐ent‐catechin (1), (−)‐ent‐epicatechin‐(4α→8)‐ent‐epicatechin (2), (epi) catechin‐(4→8)‐(epi) afzelechin‐(4→8)‐(epi) catechin (3), (+)‐epiafzelechin‐(4β→8)‐epicatechin (4), (−)‐epicatechin (5), (−)‐afzelechin‐(4α→8)‐epicatechin (6), (epi) afzelechin‐(4→8)‐(epi) afzelechin‐(4→8)‐(epi) catechin (7) and (+)‐epicatechin‐(4β→8,2β→O‐7)‐epicatechin‐(4β→8)‐catechin (C‐D1)] were found and quantified in the ethyl acetate extract of the wood samples. The second aim of this work was to improve the recovery of C‐B1 from laurel wood. The use of the fast centrifugal partition chromatography (FCPC) technique has allowed for a recovery of 96 % of a technical‐grade C‐B1 (64 % in a previous protocol using conventional column chromatography on silica gel and size‐exclusion chromatography).

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Recovery and Seasonal Variation of Cinnamtannin B‐1 from Laurel (Laurus nobilis L.) Pruning Wood Wastes ; day:18 ; month:01 ; year:2022 ; extent:1 ; Chemistry & biodiversity ; (18.01.2022) (gesamt 1)

Contributors, Places and Time

• Creator: Alejo‐Armijo, Alfonso ; Ortega‐Vidal, Juan ; Salido, Sofía ; Altarejos, Joaquín

Further information

• DOI: 10.1002/cbdv.202100807
• URN: urn:nbn:de:101:1-2022011914071690804674
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:20 AM CEST