One‐Pot Transition‐Metal‐Free Synthesis of Alkynyl Amides
Abstract: Alkynyl amides play crucial roles in organic synthesis in the production of bioactive compounds and valuable heterocycles. Despite numerous studies on their synthesis, challenges persist due to the necessity of harsh or hazardous conditions and the use of costly or unstable reagents. Herein, we present a one‐pot method for the synthesis of all three bonds of the alkyne under transition‐metal‐free conditions. An important feature of this chemistry is the use of readily available feedstock chemicals, such as methyl esters and acetamides. This approach offers efficient access to a wide range of aryl and alkyl alkynyl amides and demonstrates excellent tolerance towards various functional groups in a sustainable and cost‐effective manner.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
One‐Pot Transition‐Metal‐Free Synthesis of Alkynyl Amides ; day:06 ; month:11 ; year:2024 ; extent:9
Angewandte Chemie ; (06.11.2024) (gesamt 9)
- Urheber
-
Wu, Yu
Sátiro, Bárbara G.
Mao, Jianyou
Walsh, Patrick J.
- DOI
-
10.1002/ange.202415472
- URN
-
urn:nbn:de:101:1-2411061352212.999187324220
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:34 MESZ
Datenpartner
Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Wu, Yu
- Sátiro, Bárbara G.
- Mao, Jianyou
- Walsh, Patrick J.
Ähnliche Objekte (12)
One‐Pot Transition‐Metal‐Free Synthesis of Alkynyl Amides
Intramyometrial pregnancy after cryopreserved embryo transfer: a case report
Traction and resection in treating gastric submucosal tumor growing extraluminally by using two snares like a ropeway
The potential of coupled carbon storage and geothermal extraction in a CO2-enhanced geothermal system: a review
Early gastric mucosa-associated lymphoid tissue lymphoma treated by endoscopic submucosal dissection
Ion channel TRPM4 activity and cardiac conduction disease
Digital finance and financial literacy: An empirical investigation of Chinese households
Credit market development and firm innovation: Evidence from the People's Republic of China
Do banks price environmental risk? Evidence from a quasi natural experiment in the People's Republic of China
Multi-constrained cooperative path planning of multiple drones for persistent surveillance in urban environments
Endoscopic management of the rare situation where a gastric stromal tumor specimen falls into the nasopharynx
Rare case of intramural esophageal hematoma associated with betel nut consumption
One‐Pot Transition‐Metal‐Free Synthesis of Alkynyl Amides
Intramyometrial pregnancy after cryopreserved embryo transfer: a case report
Traction and resection in treating gastric submucosal tumor growing extraluminally by using two snares like a ropeway
The potential of coupled carbon storage and geothermal extraction in a CO2-enhanced geothermal system: a review
Early gastric mucosa-associated lymphoid tissue lymphoma treated by endoscopic submucosal dissection
Ion channel TRPM4 activity and cardiac conduction disease
Digital finance and financial literacy: An empirical investigation of Chinese households
Credit market development and firm innovation: Evidence from the People's Republic of China
Do banks price environmental risk? Evidence from a quasi natural experiment in the People's Republic of China
Multi-constrained cooperative path planning of multiple drones for persistent surveillance in urban environments
Endoscopic management of the rare situation where a gastric stromal tumor specimen falls into the nasopharynx
Rare case of intramural esophageal hematoma associated with betel nut consumption
One‐Pot Transition‐Metal‐Free Synthesis of Alkynyl Amides
Intramyometrial pregnancy after cryopreserved embryo transfer: a case report
Traction and resection in treating gastric submucosal tumor growing extraluminally by using two snares like a ropeway
The potential of coupled carbon storage and geothermal extraction in a CO2-enhanced geothermal system: a review
Early gastric mucosa-associated lymphoid tissue lymphoma treated by endoscopic submucosal dissection
Ion channel TRPM4 activity and cardiac conduction disease
Digital finance and financial literacy: An empirical investigation of Chinese households
Credit market development and firm innovation: Evidence from the People's Republic of China
Do banks price environmental risk? Evidence from a quasi natural experiment in the People's Republic of China
Multi-constrained cooperative path planning of multiple drones for persistent surveillance in urban environments
Endoscopic management of the rare situation where a gastric stromal tumor specimen falls into the nasopharynx