Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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1 Online-Ressource.
- Sprache
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Englisch
- Erschienen in
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Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells ; volume:14 ; number:12 ; day:6 ; month:12 ; year:2023 ; pages:1-15 ; date:12.2023
Cell death & disease ; 14, Heft 12 (6.12.2023), 1-15, 12.2023
- Klassifikation
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Biowissenschaften, Biologie
- Urheber
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Vogt, Melina
Dienstbier, Niklas
Schliehe-Diecks, Julian
Scharov, Katerina
Tu, Jia-Wey
Gebing, Philip
Hogenkamp, Julian
Bilen, Berna-Selin
Furlan, Silke
Picard, Daniel
Remke, Marc
Yasin, Layal
Bickel, David
Kalia, Munishikha
Iacoangeli, Alfredo
Lenz, Thomas
Stühler, Kai
Pandyra, Aleksandra A.
Hauer, Julia
Fischer, Ute
Wagener, Rabea
Borkhardt, Arndt
Bhatia, Sanil
- Beteiligte Personen und Organisationen
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SpringerLink (Online service)
- DOI
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10.1038/s41419-023-06337-3
- URN
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urn:nbn:de:101:1-2024022214153038611879
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 10:54 MESZ
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Beteiligte
- Vogt, Melina
- Dienstbier, Niklas
- Schliehe-Diecks, Julian
- Scharov, Katerina
- Tu, Jia-Wey
- Gebing, Philip
- Hogenkamp, Julian
- Bilen, Berna-Selin
- Furlan, Silke
- Picard, Daniel
- Remke, Marc
- Yasin, Layal
- Bickel, David
- Kalia, Munishikha
- Iacoangeli, Alfredo
- Lenz, Thomas
- Stühler, Kai
- Pandyra, Aleksandra A.
- Hauer, Julia
- Fischer, Ute
- Wagener, Rabea
- Borkhardt, Arndt
- Bhatia, Sanil
- SpringerLink (Online service)
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Development of Small Molecule Inhibitors Targeting HSP90 C-terminal Dimerization in BCR-ABL1 positive Leukemia
Decrypting the role of HSP90α and β isoforms in BCR-ABL1+ leukemia and Characterization of Small Molecule HSP90 Inhibitors and Degraders
The HSP90 inhibitor KW-2478 depletes the malignancy of BCR/ABL and overcomes the imatinib-resistance caused by BCR/ABL amplification
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Hsp90 depletion goes wild
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