Adult stem cells derived from skeletal muscle — biology and potential

Abstract: Skeletal muscle contains at least two distinct populations of adult stem cells — satellite cells and multipotent muscle-derived stem cells. Monopotential satellite cells are located under the basal lamina of muscle fibers. They are capable of giving rise only to cells of myogenic lineage, which play an important role in the processes of muscle regeneration. Multipotent muscle-derived stem cells are considered to be predecessors of the satellite cells. Under proper conditions, both in vitro and in vivo, they undergo myogenic, cardiogenic, chondrogenic, osteogenic and adipogenic differentiation. The main purpose of the present article is to summarize current information about adult stem cells derived from skeletal muscle, and to discuss their isolation and in vitro expansion techniques, biological properties, as well as their potential for regenerative medicine.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Adult stem cells derived from skeletal muscle — biology and potential ; volume:8 ; number:3 ; year:2013 ; pages:215-225 ; extent:11 ; Open life sciences ; 8, Heft 3 (2013), 215-225 (gesamt 11)

Contributors, Places and Time

• Creator: Danišovič, Ľuboš ; Polák, Štefan ; Vojtaššák, Ján

Further information

• DOI: 10.2478/s11535-013-0137-x
• URN: urn:nbn:de:101:1-2409211542199.299557679495
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:29 AM CEST