Community Voices and Whole-Genome Sequencing for Tuberculosis: Storytelling and the Importance of Listening

Abstract: One of the primary public health functions of a tuberculosis (TB) program is to arrest the spread of infection. Traditionally, TB programs have relied on epidemiological information, gathered through contact tracing, to infer that transmission has occurred between people. The ability of drawing such inferences is extensively context dependent. Where epidemiological information has been strong, such as 2 cases of TB occurring sequentially within a single household, confidence in such inferences is high; conversely, public health authorities have been less certain about the significance of TB cases merely occurring in the same wider social group or geographic area. Many current laboratory tests for TB used globally may be sufficient to confirm a diagnosis and guide appropriate therapy but still be insufficiently precise for distinguishing two strains reliably. In short, drawing inferences regarding a chain of transmissions has always been as much art as science.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Community Voices and Whole-Genome Sequencing for Tuberculosis: Storytelling and the Importance of Listening ; volume:27 ; number:1 ; year:2024 ; pages:68-73 ; extent:6 ; Public health genomics ; 27, Heft 1 (2024), 68-73 (gesamt 6)

Beteiligte, Orts- und Zeitangaben

• Urheber: Denholm, Justin T. ; Silva, Diego S.

Weitere Informationen

• DOI: 10.1159/000537727
• URN: urn:nbn:de:101:1-2406170755343.493228916850
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 14.08.2025, 10:52 MESZ