Nutrient-gene interactions: a single nutrient and hundreds of target genes
Abstract: Based on the effects of a selective experimental zinc deficiency in a rodent model we explore the use of transcriptome profiling for assessing nutrient-gene interactions in the liver at the molecular and cellular levels. Zinc deficiency caused pleiotropic alterations in mRNA/protein levels of hundreds of genes. In the context of observed metabolic alterations in hepatic metabolism, possible mechanisms are discussed for how a low zinc status may be sensed and transmitted into changes in various metabolic pathways. However, it also becomes obvious that analysis of such complex nutrient-gene interactions beyond the descriptional level is a real challenge for systems biology.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Nutrient-gene interactions: a single nutrient and hundreds of target genes ; volume:385 ; number:7 ; year:2004 ; pages:571-583
Biological chemistry ; 385, Heft 7 (2004), 571-583
- Creator
-
Daniel, H.
Dieck, H. tom
- DOI
-
10.1515/BC.2004.071
- URN
-
urn:nbn:de:101:1-2406121635259.111390355760
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
14.08.2025, 10:56 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Daniel, H.
- Dieck, H. tom
Other Objects (12)
Gene-nutrient interactions and susceptibility to human obesity
Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila
Air, water and nutrient interactions in paddy soils
Leaf habit and nutrient availability drive leaf nutrient resorption globally
How do chronic nutrient loading and the duration of nutrient pulses affect nutrient uptake in headwater streams?
Nutrient induced competition – use of concentrated nutrient solution for weed regulation
Nutrient elements and toxicants
Nutrient cycling in agroecosystems
Role of Gcn4p in nutrient controlled gene expression in Saccharomyces cerevisiae
Roots induce hydraulic redistribution to promote nutrient uptake and nutrient cycling in nutrient-rich but dry near-surface layers
Nutrient scoring for the DEGS1-FFQ – from food intake to nutrient intake
Plant nutrient mobilization and acquisition strategies: adaptation to water and nutrient availability
Gene-nutrient interactions and susceptibility to human obesity
Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila
Air, water and nutrient interactions in paddy soils
Leaf habit and nutrient availability drive leaf nutrient resorption globally
How do chronic nutrient loading and the duration of nutrient pulses affect nutrient uptake in headwater streams?
Nutrient induced competition – use of concentrated nutrient solution for weed regulation
Nutrient elements and toxicants
Nutrient cycling in agroecosystems
Role of Gcn4p in nutrient controlled gene expression in Saccharomyces cerevisiae
Roots induce hydraulic redistribution to promote nutrient uptake and nutrient cycling in nutrient-rich but dry near-surface layers
Nutrient scoring for the DEGS1-FFQ – from food intake to nutrient intake
Plant nutrient mobilization and acquisition strategies: adaptation to water and nutrient availability
Gene-nutrient interactions and susceptibility to human obesity
Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila
Air, water and nutrient interactions in paddy soils
Leaf habit and nutrient availability drive leaf nutrient resorption globally
How do chronic nutrient loading and the duration of nutrient pulses affect nutrient uptake in headwater streams?
Nutrient induced competition – use of concentrated nutrient solution for weed regulation
Nutrient elements and toxicants
Nutrient cycling in agroecosystems
Role of Gcn4p in nutrient controlled gene expression in Saccharomyces cerevisiae
Roots induce hydraulic redistribution to promote nutrient uptake and nutrient cycling in nutrient-rich but dry near-surface layers
Nutrient scoring for the DEGS1-FFQ – from food intake to nutrient intake