Two Very Rare Cases of Metastatic Thymic Carcinoma with Sjogren’s Syndrome: A Case Series
Thymic tumours are rare thoracic malignancies with thymic carcinoma accounting for approximately 12% of all thymic tumours compared to thymomas which account for approximately 86%. Unlike thymomas, it is very rare for thymic carcinomas to be associated with autoimmune disorders or paraneoplastic syndromes. When these phenomena do occur, the vast majority are myasthenia gravis, pure red cell aplasia, or systemic lupus erythematous. Paraneoplastic Sjogren’s syndrome is a rare complication of thymic carcinoma, with only two cases previously reported. Here we present 2 cases of patients with metastatic thymic carcinoma who developed autoimmune phenomena consistent with Sjogren’s syndrome without classical symptoms prior to treatment. One patient opted for surveillance of their malignancy, while the other underwent chemoimmunotherapy with favourable results. These case reports describe two distinctive clinical presentations of a rare paraneoplastic phenomenon.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Two Very Rare Cases of Metastatic Thymic Carcinoma with Sjogren’s Syndrome: A Case Series ; volume:16 ; number:1 ; year:2023 ; pages:122-129 ; extent:8
Case reports in oncology ; 16, Heft 1 (2023), 122-129 (gesamt 8)
- Urheber
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Smith, Amy E.
Kane, Alisa
Watts, Francesca
Qiu, Min
Chin, Venessa
- DOI
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10.1159/000529425
- URN
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urn:nbn:de:101:1-2023122723390775800562
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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2025-08-15T07:25:06+0200
Datenpartner
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Beteiligte
- Smith, Amy E.
- Kane, Alisa
- Watts, Francesca
- Qiu, Min
- Chin, Venessa