zweidimensionales bewegtes Bild
Macrophages - HIV-induced Syncytia Formation in Human Monocytes/Macrophages
With the help of time-lapse phase contrast photography (1:200 to 1:6000) it is possible to follow HIV-induced cell fusion and the formation of syncytia in monocyte/macrophages isolated from human blood. Syncytia are rarely seen in normal cell culture. The infection of monocyte/macrophages by viruses, for example human immunodeficiency virus (HIV), induces fusion between these cells which results in large multi-nucleated syncytia. In HIV-infected macrophages that have been in culture for a number of weeks these syncytia can reach a significant size and contain dozens of nuclei. The film further demonstrates not only the formation of syncytia through HIV-induced cell fusion, but also specifically the dynamics of this process, the kinetics of cell fusion and syncytia formation as well as the nature of the involvement of macrophage subtypes.
- Weitere Titel
-
Makrophagen - HIV-induzierte Synzytienbildung bei humanen Monozyten/Makrophagen
- Standort
-
Hannover TIB
- Umfang
-
126MB, 00:10:16:06 (unknown)
- Sprache
-
Englisch
- Anmerkungen
-
Audiovisuelles Material
- Erschienen in
-
Macrophages - HIV-induced Syncytia Formation in Human Monocytes/Macrophages ; (Jan. 1993)
- Schlagwort
-
macrophages
Medizin
medical microbiology
monocytes
cytopathic effect (CPE)
mononuclear phagocyte system (MPS)
cytopathological effect
syncytia
HIV
Medizinische Mikrobiologie
giant cells
medicine
- Ereignis
-
Veröffentlichung
- (wer)
-
IWF (Göttingen)
- (wann)
-
1993-01-01
- Beteiligte Personen und Organisationen
-
Briesen, Hagen von
Rübsamen-Waigmann, Helga
Kreutz, Marina
Andreesen, Reinhard
- DOI
-
10.3203/IWF/C-1815eng
- Letzte Aktualisierung
-
04.12.2024, 08:09 MEZ
Datenpartner
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Objekttyp
- zweidimensionales bewegtes Bild
Beteiligte
- Briesen, Hagen von
- Rübsamen-Waigmann, Helga
- Kreutz, Marina
- Andreesen, Reinhard
- IWF (Göttingen)
Entstanden
- 1993-01-01
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