Recent advances, challenges and updates on the development of therapeutics for malaria

Abstract: Malaria has developed as a serious worldwide health issue as a result of the introduction of resistant Plasmodium species strains. Because of the common chemo resistance to most of the existing drugs on the market, it poses a severe health problem and significant obstacles in drug research. Malaria treatment has evolved during the last two decades in response to Plasmodium falciparum drug sensitivity and a return of the disease in tropical areas. Plasmodium falciparum is now highly resistant to the majority of antimalarial drugs. The parasite resistance drew focus to developing novel antimalarials to combat parasite resistance. The requirement for many novel antimalarial drugs in the future year necessitates adopting various drug development methodologies. Different innovative strategies for discovering antimalarial drugs are now being examined here. This review is primarily concerned with the description of newly synthesized antimalarial compounds, i.e. Tafenoquine, Cipargamin, Fe.... https://www.excli.de/index.php/excli/article/view/6856

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Recent advances, challenges and updates on the development of therapeutics for malaria ; volume:23 ; year:2024 ; EXCLI journal ; 23 (2024)

Contributors, Places and Time

• Creator: Nandal, Rimmy ; Kumar, Davinder ; Aggarwal, Navidha ; Kumar, Virender ; Narasimhan, Balasubramanian ; Marwaha, Rakesh Kumar ; Sharma, Prabodh Chander ; Kumar, Surender ; Bansal, Nitin ; Chopra, Hitesh ; Deep, Aakash

Further information

• DOI: 10.17179/excli2023-6856
• URN: urn:nbn:de:101:1-2406210313564.325904404393
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:48 AM CEST