In silico approaches supporting drug repurposing for Leishmaniasis : a scoping review
Abstract: The shortage of treatment options for leishmaniasis, especially those easy to administer and viable for deployment in the world's poorest regions, highlights the importance of employing these strategies to cost-effectively investigate repurposing candidates. This scoping review aims to map the studies using in silico methodologies for drug repurposing against leishmaniasis. This study followed JBI recommendations for scoping reviews. Articles were searched on PubMed, Scopus, and Web of Science databases using keywords related to leishmaniasis and in silico methods for drug discovery, without publication date restrictions. The selection was based on primary studies involving computational methods for antileishmanial drug repurposing. Information about methodologies, obtained data, and outcomes were extracted. After the full-text appraisal, 34 studies were included in this review. Molecular docking was the preferred method for evaluating repurposing candidates (n=25). Studies reporte.... https://www.excli.de/excli/article/view/7552
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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In silico approaches supporting drug repurposing for Leishmaniasis ; volume:23 ; year:2024
EXCLI journal ; 23 (2024)
- Creator
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Scheiffer, Gustavo
Domingues, Karime Zeraik Abdalla
Gorski, Daniela
Cobre, Alexandre de Fátima
Lazo, Raul Edison Luna
Borba, Helena Hiemisch Lobo
Ferreira, Luana Mota
Pontarolo, Roberto
- DOI
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10.17179/excli2024-7552
- URN
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urn:nbn:de:101:1-2411080215497.343686371165
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:27 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Scheiffer, Gustavo
- Domingues, Karime Zeraik Abdalla
- Gorski, Daniela
- Cobre, Alexandre de Fátima
- Lazo, Raul Edison Luna
- Borba, Helena Hiemisch Lobo
- Ferreira, Luana Mota
- Pontarolo, Roberto
Other Objects (12)
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Network-based approach to prediction and population-based validation of in silico drug repurposing
Drug repurposing
Krankendarstellung: Leishmaniasis
Krankendarstellung: Leishmaniasis
In silico repurposing of antipsychotic drugs for Alzheimer’s disease
Repurposing metformin as a potential anticancer agent using in silico technique
Psychosocial burden of localised cutaneous Leishmaniasis: a scoping review
Supporting family care: a scoping app review
Computational drug repurposing based on electronic health records: a scoping review
In silico drug repurposing identifies mebendazole as a treatment option for chemoresistant hepatoblastoma
Unlocking potential inhibitors for Bruton's tyrosine kinase through in-silico drug repurposing strategies
In Silico drug repurposing pipeline using deep learning and structure based approaches in epilepsy
Network-based approach to prediction and population-based validation of in silico drug repurposing
Drug repurposing
Krankendarstellung: Leishmaniasis
Krankendarstellung: Leishmaniasis
In silico repurposing of antipsychotic drugs for Alzheimer’s disease
Repurposing metformin as a potential anticancer agent using in silico technique
Psychosocial burden of localised cutaneous Leishmaniasis: a scoping review
Supporting family care: a scoping app review
Computational drug repurposing based on electronic health records: a scoping review
In silico drug repurposing identifies mebendazole as a treatment option for chemoresistant hepatoblastoma
Unlocking potential inhibitors for Bruton's tyrosine kinase through in-silico drug repurposing strategies
In Silico drug repurposing pipeline using deep learning and structure based approaches in epilepsy
Network-based approach to prediction and population-based validation of in silico drug repurposing
Drug repurposing
Krankendarstellung: Leishmaniasis