Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2045-2322

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia ; volume:8 ; number:1 ; day:26 ; month:7 ; year:2018 ; pages:1-13 ; date:12.2018
Scientific reports ; 8, Heft 1 (26.7.2018), 1-13, 12.2018

Creator: Hornung, Roman

Contributor: Jurinovic, Vindi
Batcha, Aarif M. N.
Bamopoulos, Stefanos A.
Rothenberg-Thurley, Maja
Amler, Susanne
Sauerland, Maria Cristina
Berdel, Wolfgang E.
Wörmann, Bernhard J.
Bohlander, Stefan K.
Braess, Jan
Hiddemann, Wolfgang
Lehmann, Sören
Mareschal, Sylvain
Spiekermann, Karsten
Metzeler, Klaus H.
Herold, Tobias
Boulesteix, Anne-Laure
SpringerLink (Online service)

DOI: 10.1038/s41598-018-29593-2

URN: urn:nbn:de:101:1-2018092322385714547818

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:27 AM CEST

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Associated

Hornung, Roman
Jurinovic, Vindi
Batcha, Aarif M. N.
Bamopoulos, Stefanos A.
Rothenberg-Thurley, Maja
Amler, Susanne
Sauerland, Maria Cristina
Berdel, Wolfgang E.
Wörmann, Bernhard J.
Bohlander, Stefan K.
Braess, Jan
Hiddemann, Wolfgang
Lehmann, Sören
Mareschal, Sylvain
Spiekermann, Karsten
Metzeler, Klaus H.
Herold, Tobias
Boulesteix, Anne-Laure
SpringerLink (Online service)

Other Objects (12)

Hochschulschrift

RUNX1 mutations in acute myeloid leukemia

Monitoring Minimal Residual Disease in RUNX1 -Mutated Acute Myeloid Leukemia

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia

MiR144/451 expression is repressed by RUNX1 during megakaryopoiesis and disturbed by RUNX1/ETO

Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

RUNX1 gene expression in Egyptian acute myeloid leukemia patients: may it have therapeutic implications?

Establishment of a Novel Technique Termed GIPFEL to Determine the Frequency of ETV6-RUNX1 Fusions in Healthy Newborns and Analysis of Cooperating Oncogenic Lesions Leading to ETV6-RUNX1 Positive Childhood Leukemia

Hochschulschrift

RUNX1-Mutationen bei Patienten mit akuter myeloischer Leukämie

Identifizierung von Zielgenen des chimären Transkriptionsfaktors ETV6/RUNX1

Hochschulschrift

RUNX1 mutations in acute myeloid leukemia

Monitoring Minimal Residual Disease in RUNX1 -Mutated Acute Myeloid Leukemia

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia

MiR144/451 expression is repressed by RUNX1 during megakaryopoiesis and disturbed by RUNX1/ETO

Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

RUNX1 gene expression in Egyptian acute myeloid leukemia patients: may it have therapeutic implications?

Establishment of a Novel Technique Termed GIPFEL to Determine the Frequency of ETV6-RUNX1 Fusions in Healthy Newborns and Analysis of Cooperating Oncogenic Lesions Leading to ETV6-RUNX1 Positive Childhood Leukemia

Hochschulschrift

RUNX1-Mutationen bei Patienten mit akuter myeloischer Leukämie

Identifizierung von Zielgenen des chimären Transkriptionsfaktors ETV6/RUNX1

Hochschulschrift

RUNX1 mutations in acute myeloid leukemia

Monitoring Minimal Residual Disease in RUNX1 -Mutated Acute Myeloid Leukemia

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia

MiR144/451 expression is repressed by RUNX1 during megakaryopoiesis and disturbed by RUNX1/ETO

Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

RUNX1 gene expression in Egyptian acute myeloid leukemia patients: may it have therapeutic implications?

Establishment of a Novel Technique Termed GIPFEL to Determine the Frequency of ETV6-RUNX1 Fusions in Healthy Newborns and Analysis of Cooperating Oncogenic Lesions Leading to ETV6-RUNX1 Positive Childhood Leukemia

Hochschulschrift

RUNX1-Mutationen bei Patienten mit akuter myeloischer Leukämie

Identifizierung von Zielgenen des chimären Transkriptionsfaktors ETV6/RUNX1

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Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia

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Other Objects (12)

RUNX1 mutations in acute myeloid leukemia

Monitoring Minimal Residual Disease in RUNX1 -Mutated Acute Myeloid Leukemia

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia

MiR144/451 expression is repressed by RUNX1 during megakaryopoiesis and disturbed by RUNX1/ETO

Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

RUNX1 gene expression in Egyptian acute myeloid leukemia patients: may it have therapeutic implications?

Establishment of a Novel Technique Termed GIPFEL to Determine the Frequency of ETV6-RUNX1 Fusions in Healthy Newborns and Analysis of Cooperating Oncogenic Lesions Leading to ETV6-RUNX1 Positive Childhood Leukemia

RUNX1-Mutationen bei Patienten mit akuter myeloischer Leukämie

Identifizierung von Zielgenen des chimären Transkriptionsfaktors ETV6/RUNX1

RUNX1 mutations in acute myeloid leukemia

Monitoring Minimal Residual Disease in RUNX1 -Mutated Acute Myeloid Leukemia

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia

MiR144/451 expression is repressed by RUNX1 during megakaryopoiesis and disturbed by RUNX1/ETO

Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

RUNX1 gene expression in Egyptian acute myeloid leukemia patients: may it have therapeutic implications?

Establishment of a Novel Technique Termed GIPFEL to Determine the Frequency of ETV6-RUNX1 Fusions in Healthy Newborns and Analysis of Cooperating Oncogenic Lesions Leading to ETV6-RUNX1 Positive Childhood Leukemia

RUNX1-Mutationen bei Patienten mit akuter myeloischer Leukämie

Identifizierung von Zielgenen des chimären Transkriptionsfaktors ETV6/RUNX1

RUNX1 mutations in acute myeloid leukemia

Monitoring Minimal Residual Disease in RUNX1 -Mutated Acute Myeloid Leukemia

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia

MiR144/451 expression is repressed by RUNX1 during megakaryopoiesis and disturbed by RUNX1/ETO

Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

RUNX1 gene expression in Egyptian acute myeloid leukemia patients: may it have therapeutic implications?

Establishment of a Novel Technique Termed GIPFEL to Determine the Frequency of ETV6-RUNX1 Fusions in Healthy Newborns and Analysis of Cooperating Oncogenic Lesions Leading to ETV6-RUNX1 Positive Childhood Leukemia

RUNX1-Mutationen bei Patienten mit akuter myeloischer Leukämie

Identifizierung von Zielgenen des chimären Transkriptionsfaktors ETV6/RUNX1

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