Interactions Between Peptide Assemblies and Proteins for Medicine

Abstract: Peptide assembly is attractive not only to develop biotechnological tools and smart nanomaterials, but also to treat pathologies in new ways. This Review focuses on recent progress made in the exciting area pertaining the interaction between peptide assemblies and proteins. Earlier works aimed to identify proteins able to bind peptide assemblies for therapeutics’ delivery and biocompatible scaffolds. Recent advancements cover more applications that go beyond tissue regeneration and biomaterials. On one hand, self‐assembling peptides interacting with proteins can inhibit pathological amyloid fibrillation, or boost the immune response to vaccines. On the other, they have been exploited to promote protein crystallization, also for therapeutics’ delivery. As research advances in this exciting area, it opens the way towards a qualitative leap in the clinical translation of supramolecular medicinal chemistry to creatively tackle unmet challenges of modern disease treatment and prevention.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Interactions Between Peptide Assemblies and Proteins for Medicine ; day:20 ; month:06 ; year:2022 ; extent:1
Israel journal of chemistry ; (20.06.2022) (gesamt 1)

Creator
Mañas‐Torres, Mari C.
Illescas‐Lopez, Sara
Gavira, José A.
de Cienfuegos, Luis Álvarez
Marchesan, Silvia

DOI
10.1002/ijch.202200018
URN
urn:nbn:de:101:1-2022062015275541883688
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:34 AM CEST

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Associated

  • Mañas‐Torres, Mari C.
  • Illescas‐Lopez, Sara
  • Gavira, José A.
  • de Cienfuegos, Luis Álvarez
  • Marchesan, Silvia

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