Diterpene Biosynthesis from Geranylgeranyl Diphosphate Analogues with Changed Reactivities Expands Skeletal Diversity
Abstract: Two analogues of the diterpene precursor geranylgeranyl diphosphate with shifted double bonds, named iso‐GGPP I and iso‐GGPP II, were enzymatically converted with twelve diterpene synthases from bacteria, fungi and protists. The changed reactivity in the substrate analogues resulted in the formation of 28 new diterpenes, many of which exhibit novel skeletons.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Diterpene Biosynthesis from Geranylgeranyl Diphosphate Analogues with Changed Reactivities Expands Skeletal Diversity ; day:21 ; month:09 ; year:2022 ; extent:1
Angewandte Chemie / International edition. International edition ; (21.09.2022) (gesamt 1)
- Creator
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Li, Heng
Dickschat, Jeroen S.
- DOI
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10.1002/anie.202211054
- URN
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urn:nbn:de:101:1-2022092215062751114179
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:36 AM CEST
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Associated
- Li, Heng
- Dickschat, Jeroen S.
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