Exocrine drainage of the transplanted pancreas: A review

Pancreas transplant is an important treatment option for insulin dependent diabetic patients as it may result in physiologic euglycemia. Improvements in surgical technique, graft preservation, immunosuppression, diagnosis and management of rejection, and management of post-transplant complications have led to improved patient survival. There are several technical variables to consider when performing a pancreas transplant. One is the type of exocrine drainage to be used. The most common types of exocrine drainage are enteric or bladder drainage. Gastric- exocrine drainage has also been recently introduced. The most commonly cited complications associated with bladder drainage include metabolic complications, urologic complications and the need for enteric conversion. Many complications related to bladder drainage can be managed non-operatively with Foley catheter drainage. For those complications that cannot be managed in this manner, enteric conversion is an option. Complications associated with enteric drainage include anastomotic leak and intra-abdominal abscess, although at rates lower than cited in the early literature on the topic. Bladder drainage of exocrine secretions and enteric drainage of exocrine secretions, or a staged procedure with bladder drainage followed by indicated or elective enteric conversion are reasonable options for drainage of the exocrine secretions of the pancreas. Gastric-exocrine drainage is a promising therapy deserving of future exploration.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Exocrine drainage of the transplanted pancreas: A review ; volume:09 ; number:03 ; year:2017 ; pages:52-63
Ibnosina journal of medicine and biomedical sciences ; 09, Heft 03 (2017), 52-63

Contributor
Beal, Eliza
El-Hinnawi, Ashraf
Whitson, Bryan
Elkhammas, Elmahdi
Henry, Mitchell
Black, Sylvester

DOI
10.4103/1947-489X.210111
URN
urn:nbn:de:101:1-2022101003291600849480
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:20 AM CEST

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Associated

  • Beal, Eliza
  • El-Hinnawi, Ashraf
  • Whitson, Bryan
  • Elkhammas, Elmahdi
  • Henry, Mitchell
  • Black, Sylvester

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