Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1750-1326

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction ; volume:4 ; number:1 ; day:09 ; month:2 ; year:2009 ; pages:1-12 ; date:12.2009
Molecular neurodegeneration ; 4, Heft 1 (09.2.2009), 1-12, 12.2009

Creator: Weiss, Andreas

Contributor: Roscic, Ana
Paganetti, Paolo
SpringerLink (Online service)

DOI: 10.1186/1750-1326-4-11

URN: urn:nbn:de:1111-2016073064549

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:58 AM CEST

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Weiss, Andreas
Roscic, Ana
Paganetti, Paolo
SpringerLink (Online service)

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Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease

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Analysis of mutant huntingtin aggregation and toxicity in Drosophila models of Huntington’s disease

Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia

Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease

Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Analysis of mutant and total huntingtin expression in Huntington’s disease murine models

Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease

Hochschulschrift

Analysis of mutant huntingtin aggregation and toxicity in Drosophila models of Huntington’s disease

Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia

Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease

Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Analysis of mutant and total huntingtin expression in Huntington’s disease murine models

Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease

Hochschulschrift

Analysis of mutant huntingtin aggregation and toxicity in Drosophila models of Huntington’s disease

Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia

Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease

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Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction

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Other Objects (12)

Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Analysis of mutant and total huntingtin expression in Huntington’s disease murine models

Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease

Analysis of mutant huntingtin aggregation and toxicity in Drosophila models of Huntington’s disease

Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia

Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease

Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Analysis of mutant and total huntingtin expression in Huntington’s disease murine models

Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease

Analysis of mutant huntingtin aggregation and toxicity in Drosophila models of Huntington’s disease

Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia

Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease

Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Analysis of mutant and total huntingtin expression in Huntington’s disease murine models

Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease

Analysis of mutant huntingtin aggregation and toxicity in Drosophila models of Huntington’s disease

Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia

Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease

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