Insights into the mechanism of the PIK3CA E545K activating mutation using MD simulations

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2045-2322

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Insights into the mechanism of the PIK3CA E545K activating mutation using MD simulations ; volume:8 ; number:1 ; day:19 ; month:10 ; year:2018 ; pages:1-16 ; date:12.2018
Scientific reports ; 8, Heft 1 (19.10.2018), 1-16, 12.2018

Classification: Biowissenschaften, Biologie

Creator: Leontiadou, Hari

Contributor: Galdadas, Ioannis
Athanasiou, Christina
Cournia, Zoe
SpringerLink (Online service)

DOI: 10.1038/s41598-018-27044-6

URN: urn:nbn:de:101:1-2018112100291056114474

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:55 AM CEST

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Leontiadou, Hari
Galdadas, Ioannis
Athanasiou, Christina
Cournia, Zoe
SpringerLink (Online service)

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Insights into the mechanism of the PIK3CA E545K activating mutation using MD simulations

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Other Objects (12)

Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2–, PIK3CA-mutated breast cancers

PIK3CA-activating mutations and chemotherapy sensitivity in stage II–III breast cancer

PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations

Pulmonary artery mass with PIK3CA mutation after orthotopic heart transplantation

The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR

Diagnostic application of PIK3CA mutation analysis in Chinese esophageal cancer patients

Carcinogenesis of PIK3CA

Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas

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A case report of FAVA syndrome in a young woman carrying a mutation in the PIK3CA gene

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Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2–, PIK3CA-mutated breast cancers

PIK3CA-activating mutations and chemotherapy sensitivity in stage II–III breast cancer

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Carcinogenesis of PIK3CA

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The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR

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Carcinogenesis of PIK3CA

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A case report of FAVA syndrome in a young woman carrying a mutation in the PIK3CA gene

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