An antioxidant probiotic reduces postprandial lipemia and oxidative stress
Abstract: Reducing postprandial oxidative stress (OxS), decreasing postprandial blood triglyceride level (TG) and improving lipoprotein status is likely to have a preventive impact on the development of cardiovascular disease (CVD). Previously we have shown that the antioxidant probiotic Lactobacillus fermentum ME-3 (DSM14241) is characterized by antiatherogenic effects. This randomized double-blind placebo-controlled study evaluated the influence of kefir enriched with an antioxidative probiotic L. fermentum ME-3 (LfKef) on postprandial OxS, blood TG response and lipoprotein status. 100 clinically healthy subjects were recruited into the study. Blood parameters of postprandial OxS, TG and lipoprotein status were determined by oxidized LDL, baseline diene conjugation in LDL (BDC-LDL), oxidized LDL complex with beta-2 glycoprotein (Beta2-GPI-oxLDL), paraoxonase (PON) activity, LDL-Chol, HDL-Chol and TG. To evaluate general body postprandial OxS-load we measured 8-isoprostanes (8-EPI) in the urine. Consumption of LfKef significantly reduced the postprandial level of oxidized LDL, BDC-LDL, Beta2-GPI-oxLDL, urinary 8-isoprostanes and postprandial TG and caused a significant increase in HDL-Chol and PON activity. This is the first evidence that kefir enriched with an antioxidant probiotic may have a positive effect on both postprandial OxS and TG response as well as on lipoprotein status.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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An antioxidant probiotic reduces postprandial lipemia and oxidative stress ; volume:6 ; number:1 ; year:2011 ; pages:32-40 ; extent:9
Open life sciences ; 6, Heft 1 (2011), 32-40 (gesamt 9)
- Creator
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Kullisaar, Tiiu
Shepetova, Jelena
Zilmer, Kersti
Songisepp, Epp
Rehema, Aune
Mikelsaar, Marika
Zilmer, Mihkel
- DOI
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10.2478/s11535-010-0103-4
- URN
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urn:nbn:de:101:1-2409201904179.573581434429
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:32 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Kullisaar, Tiiu
- Shepetova, Jelena
- Zilmer, Kersti
- Songisepp, Epp
- Rehema, Aune
- Mikelsaar, Marika
- Zilmer, Mihkel
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Single vagus nerve stimulation reduces early postprandial C-peptide levels but not other hormones or postprandial metabolism
Impact of short-term dietary modification on postprandial oxidative stress
Antimicrobial and antioxidant activities of Saccharomyces cerevisiae IFST062013, a potential probiotic
Daily Probiotic Ayran Intake Reduces Gingival Inflammation: An Experimental Gingivitis Study
Nutritional load in post-prandial oxidative stress and the pathogeneses of diabetes mellitus
Four weeks of probiotic supplementation reduces GI symptoms during a marathon race
Enhancing ergogenic performance and antioxidant benefits of red sugarcane juice through probiotic fermentation
Exercise and postprandial lipaemia: effects on peripheral vascular function, oxidative stress and gastrointestinal transit
Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals
Antioxidant rich grape pomace extract suppresses postprandial hyperglycemia in diabetic mice by specifically inhibiting alpha-glucosidase
Paricalcitol reduces oxidative stress and inflammation in hemodialysis patients
Women experience lower postprandial oxidative stress compared to men
Single vagus nerve stimulation reduces early postprandial C-peptide levels but not other hormones or postprandial metabolism
Impact of short-term dietary modification on postprandial oxidative stress
Antimicrobial and antioxidant activities of Saccharomyces cerevisiae IFST062013, a potential probiotic
Daily Probiotic Ayran Intake Reduces Gingival Inflammation: An Experimental Gingivitis Study
Nutritional load in post-prandial oxidative stress and the pathogeneses of diabetes mellitus
Four weeks of probiotic supplementation reduces GI symptoms during a marathon race
Enhancing ergogenic performance and antioxidant benefits of red sugarcane juice through probiotic fermentation
Exercise and postprandial lipaemia: effects on peripheral vascular function, oxidative stress and gastrointestinal transit
Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals
Antioxidant rich grape pomace extract suppresses postprandial hyperglycemia in diabetic mice by specifically inhibiting alpha-glucosidase