Comparison of laparoscopy and open radical nephrectomy of renal cell cancer

Objective: The aim of this study was to summarize the current evidence to evaluate the effects of laparoscopic radical nephrectomy (LRN) and open radical nephrectomy (ORN) in the treatment of renal cell carcinoma. Methods: A comprehensive literature search was performed using PubMed, Embase and Google Scholar to identify all relevant studies. 8 published studies were included in this meta-analysis. We pooled the odds ratios (OR), standardised mean difference (SMD) and conducted heterogeneity, and quality assessment. Results: The outcome of treatment effects included surgical blood loss, surgical time, postoperative complications, and post-operative length of hospital stay. Comparing open radical nephrectomy for kidney cancer patients, the pooled SMD of surgical time was 0.47, (95% confidential index CI = [0.09, 0.85]), the pooled SMD of operative blood loss was -68.98, (95% CI = [-99.63, -38.34]), the pooled SMD of post-operative length of hospital stay was -4.32, (95% CI = [-4.62, -4.03]), and the pooled OR of postoperative complications was 0.52, (95% CI = [0.30, 0.91]). Conclusion: LRN was found to significantly decrease patients’ blood loss. In addition, LRN offers less post-operative length of hospital stay.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Comparison of laparoscopy and open radical nephrectomy of renal cell cancer ; volume:14 ; number:1 ; year:2019 ; pages:392-397 ; extent:6
Open medicine ; 14, Heft 1 (2019), 392-397 (gesamt 6)

Creator
Wang, Dong
Xiao, Zejun
Shou, Jianzhong
Li, Changling
Xing, Nianzeng

DOI
10.1515/med-2019-0040
URN
urn:nbn:de:101:1-2022101114141902390674
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:25 AM CEST

Data provider

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Associated

  • Wang, Dong
  • Xiao, Zejun
  • Shou, Jianzhong
  • Li, Changling
  • Xing, Nianzeng

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