Chemoenzymatic Cascades Combining Biocatalysis and Transition Metal Catalysis for Asymmetric Synthesis

Abstract: The combination of catalytic methods provides multiple advantages in organic synthesis, allowing access to diverse organic molecules in a straightforward manner. Merging metal and enzyme catalysis is currently receiving great attention due to the possibility to assemble metal catalysis in C−C coupling, olefin metathesis, hydration and other reactions with the exquisite stereospecificity displayed by enzymes. Thus, this minireview is organized based on the action of the metal species (Pd, Ru, Au, Ir, Fe…) in combination with different enzymes. Special attention will be paid to the design of sequential processes and concurrent cascades, presenting solutions such as the use of surfactants or compartmentalization strategies for those cases where incompatibilities could hamper the overall process.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Chemoenzymatic Cascades Combining Biocatalysis and Transition Metal Catalysis for Asymmetric Synthesis ; day:28 ; month:02 ; year:2023 ; extent:16
Angewandte Chemie ; (28.02.2023) (gesamt 16)

Urheber
González‐Granda, Sergio
Escot, Lorena
Lavandera, Iván
Gotor‐Fernández, Vicente

DOI
10.1002/ange.202217713
URN
urn:nbn:de:101:1-2023022814340477601294
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 11:02 MESZ

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Beteiligte

  • González‐Granda, Sergio
  • Escot, Lorena
  • Lavandera, Iván
  • Gotor‐Fernández, Vicente

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