Hepatotoxicity of nanomaterials: From mechanism to therapeutic strategy
Abstract: Most nanoparticles are metabolized and accumulated in the liver; therefore, this review, based on most data collected from PubMed.gov between 2012 and 2023 with the keywords “nanomaterials induced hepatotoxicity,” aims to elucidate the mechanism of nanoparticles leading to liver injury and propose relevant strategies. We discuss the biomedical approaches and strategies for mitigating liver injury, including 1) principle and recommendation of material selection; 2) nanoparticle surface modulation; 3) strategies inspired by virus and other biological phenomenon; and 4) drug and other possible adjunctive strategies. The optimal design of nanomaterials and therapeutic strategies to attenuate hepatotoxicity is critical for the development of nanomedicine.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Hepatotoxicity of nanomaterials: From mechanism to therapeutic strategy ; volume:13 ; number:1 ; year:2024 ; extent:14
Nanotechnology reviews ; 13, Heft 1 (2024) (gesamt 14)
- Urheber
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Gao, Chengtian
Wang, Mingdong
Zheng, Yali
Zhang, Liang
He, Jiawei
Liu, Bosen
Lin, Xinhua
Mao, Jingsong
Wang, Zhanxiang
- DOI
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10.1515/ntrev-2024-0074
- URN
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urn:nbn:de:101:1-2408081540553.654862708893
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 10:53 MESZ
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Beteiligte
- Gao, Chengtian
- Wang, Mingdong
- Zheng, Yali
- Zhang, Liang
- He, Jiawei
- Liu, Bosen
- Lin, Xinhua
- Mao, Jingsong
- Wang, Zhanxiang
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