Prevalence and predictors of adequate treatment of overt hypothyroidism – a population-based study

Abstract: The aim of this study is to evaluate the adequacy of treatment, and to identify factors influencing treatment of hypothyroidism. Patients newly diagnosed with overt hypothyroidism (n=345) were identified via a register linked to a laboratory database. In selected periods with staff available, 165 patients were invited, and 113 (68.5 %) accepted participating in a comprehensive program including blood tests and completion of questionnaires. We performed a longitudinal follow-up on thyroid function tests 10 years after the diagnosis. Time to reach a serum TSH level of 0.2-10 mU/L (termed as clinically acceptable) and biochemical normalization (TSH: 0.2-5.0 mU/L), respectively, were analyzed using Kaplan Meier survival analysis. Predictors for longer duration to reach the normal TSH range were identified using cox proportional hazards regression. Only 67.7 % of the patients were in the euthyroid range on the long term after diagnosis of overt hypothyroidism (2 years: 59.4 %; 10 years:.... https://www.excli.de/index.php/excli/article/view/4291

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Prevalence and predictors of adequate treatment of overt hypothyroidism – a population-based study ; volume:21 ; day:06 ; month:01 ; year:2022 ; EXCLI journal ; 21 (06.01.2022)

Contributors, Places and Time

• Creator: Lindgård Nielsen, Julie ; Karmisholt, Jesper ; Bülow Pedersen, Inge ; Carlé, Allan

Further information

• DOI: 10.17179/excli2021-4291
• URN: urn:nbn:de:101:1-2022020402134268413401
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:21 AM CEST