Parkinson's disease effect on autonomic modulation: an analysis using geometric indices
Abstract: Background: Parkinson's disease (PD) produces autonomic changes, indicating lower parasympathetic modulation and global variability, but these changes need further studying regarding geometric methods. Objective: To investigate the autonomic modulation in individuals with PD using heart rate variability (HRV) indices obtained through geometric methods. Methods: This is a cross-sectional study that assessed 50 individuals, split into two groups: PD group (PDG; n=26; 75.36±5.21 years) and control group (CG; n=24; 75.36±5.21 years). We evaluated the autonomic modulation by measuring the heart rate beat-to-beat for 30 min with the individual in supine rest using a heart rate monitor and assessed geometric indices (RRtri, TINN, SD1, SD2, SD1/SD2 ratio, and qualitative analysis of the Poincaré plot). Results: Significant reductions were found in RRtri, TINN, SD1, and SD2 indices among PDG compared to CG. Regarding the SD1/SD2 ratio, no significant changes were detected between the groups. The Poincaré plot demonstrated that individuals with PD had lower beat-to-beat dispersion in RR intervals, in addition to greater long-term dispersion of RR intervals compared to CG. Conclusions: The results suggest a reduction in the parasympathetic autonomic modulation and global variability in individuals with PD compared to controls, regardless of sex, age, and body mass index.
- Alternative title
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Efeito da doença de Parkinson na modulação autonômica: análise por meio de índices geométricos
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Parkinson's disease effect on autonomic modulation: an analysis using geometric indices ; volume:79 ; number:02 ; year:2021 ; pages:114-121
Arquivos de neuro-psiquiatria ; 79, Heft 02 (2021), 114-121
- Contributor
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Stoco-Oliveira, Mileide Cristina
Ricci-Vitor, Ana Laura
Vanzella, Laís Manata
Valente, Heloisa Balotari
Silva, Vitor Eduardo dos Santos
André, Larissa Borba
Carvalho, Augusto Cesinando de
Garner, David Matthew
Vanderlei, Luiz Carlos Marques
- DOI
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10.1590/0004-282X-anp-2020-0088
- URN
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urn:nbn:de:101:1-2023081711105587315847
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:50 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Stoco-Oliveira, Mileide Cristina
- Ricci-Vitor, Ana Laura
- Vanzella, Laís Manata
- Valente, Heloisa Balotari
- Silva, Vitor Eduardo dos Santos
- André, Larissa Borba
- Carvalho, Augusto Cesinando de
- Garner, David Matthew
- Vanderlei, Luiz Carlos Marques
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