Diastereoselective Synthesis of Cyclopenta (c) furans by a Catalytic Multicomponent Reaction

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Abstract: A diastereoselective three‐component reaction between alkynyl enones, aldehydes and secondary amines is reported. With the aid of a benign indium catalyst, a range of highly substituted cyclopenta[c]furan derivatives can be obtained in a single‐step procedure. The formation of the stereodefined heterocyclic motifs takes place via in situ generation of enamines followed by two sequential cyclization steps.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Diastereoselective Synthesis of Cyclopenta (c) furans by a Catalytic Multicomponent Reaction ; volume:55 ; number:39 ; year:2016 ; pages:11863-11866 ; extent:4
Angewandte Chemie / International edition. International edition ; 55, Heft 39 (2016), 11863-11866 (gesamt 4)

Creator: Pathipati, Stalin R.
van der Werf, Angela
Eriksson, Lars
Selander, Nicklas

DOI: 10.1002/anie.201606108

URN: urn:nbn:de:101:1-2022101307470378389380

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:29 AM CEST

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Pathipati, Stalin R.
van der Werf, Angela
Eriksson, Lars
Selander, Nicklas

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