Additively Manufactured Zn‐2Mg Alloy Porous Scaffolds with Customizable Biodegradable Performance and Enhanced Osteogenic Ability
Abstract: The combination of bioactive Zn‐2Mg alloy and additively manufactured porous scaffold is expected to achieve customizable biodegradable performance and enhanced bone regeneration. Herein, Zn‐2Mg alloy scaffolds with different porosities, including 40% (G‐40‐2), 60% (G‐60‐2), and 80% (G‐80‐2), and different unit sizes, including 1.5 mm (G‐60‐1.5), 2 mm (G‐60‐2), and 2.5 mm (G‐60‐2.5), are manufactured by a triply periodic minimal surface design and a reliable laser powder bed fusion process. With the same unit size, compressive strength (CS) and elastic modulus (EM) of scaffolds substantially decrease with increasing porosities. With the same porosity, CS and EM just slightly decrease with increasing unit sizes. The weight loss after degradation increases with increasing porosities and decreasing unit sizes. In vivo tests indicate that Zn‐2Mg alloy scaffolds exhibit satisfactory biocompatibility and osteogenic ability. The osteogenic ability of scaffolds is mainly determined by their physical and chemical characteristics. Scaffolds with lower porosities and smaller unit sizes show better osteogenesis due to their suitable pore size and larger surface area. The results indicate that the biodegradable performance of scaffolds can be accurately regulated on a large scale by structure design and the additively manufactured Zn‐2Mg alloy scaffolds have improved osteogenic ability for treating bone defects.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Additively Manufactured Zn‐2Mg Alloy Porous Scaffolds with Customizable Biodegradable Performance and Enhanced Osteogenic Ability ; day:07 ; month:12 ; year:2023 ; extent:13
Advanced science ; (07.12.2023) (gesamt 13)
- Creator
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Wang, Xuan
Liu, Aobo
Zhang, Zhenbao
Hao, Dazhong
Liang, Yijie
Dai, Jiabao
Jin, Xiang
Deng, Huanze
Zhao, Yantao
Wen, Peng
Li, Yanfeng
- DOI
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10.1002/advs.202307329
- URN
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urn:nbn:de:101:1-2023120814382405812222
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:22 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Wang, Xuan
- Liu, Aobo
- Zhang, Zhenbao
- Hao, Dazhong
- Liang, Yijie
- Dai, Jiabao
- Jin, Xiang
- Deng, Huanze
- Zhao, Yantao
- Wen, Peng
- Li, Yanfeng
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