The breakthrough and the future: CD20 chimeric antigen receptor T‐cell therapy for hematologic malignancies

Abstract: Chimeric antigen receptors (CAR) T‐cell therapy is one of the most effective treatments in curing hematologic malignancies. Besides the four CD19 CAR T‐cells therapy recently approved by the US Food and Drug Administration (FDA), CD20 CAR T‐cell therapy is now another effective treatment option for relapsed or refractory non‐Hodgkin lymphoma (NHL). CD20 CAR T‐cell infusion has achieved remarkable clinical outcomes in patients with B‐cell malignancies. This review will cover the current situations, advantages, limitations, prospects, and application of CD20 CAR T‐cell therapy.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
The breakthrough and the future: CD20 chimeric antigen receptor T‐cell therapy for hematologic malignancies ; day:05 ; month:10 ; year:2022 ; extent:7
ImmunoMedicine ; (05.10.2022) (gesamt 7)

Creator
Tan Su Yin, Elaine
Hu, Yong Xian
Huang, He

DOI
10.1002/imed.1039
URN
urn:nbn:de:101:1-2022100515035970974255
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:26 AM CEST

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Associated

  • Tan Su Yin, Elaine
  • Hu, Yong Xian
  • Huang, He

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