Photocatalytic α‐Difluoroalkoxyketones Synthesis via Radical Intermolecular Alkoxylation of Difluoroenol Silyl Ethers
Abstract: We present a metal‐free photocatalytic approach for the synthesis of difluoroalkoxylatedketones. This strategy involves the generation of alkoxyl radicals from pyridinium salts upon the activity of a catalytic electron‐donor‐acceptor (EDA) complex. This mild process tolerates several functional groups and can be scaled up to gram scale. Diverse products manipulations accounts for the versatility of the obtained fluorinated products, highlighting the synthetic usefulness of this method.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Photocatalytic α‐Difluoroalkoxyketones Synthesis via Radical Intermolecular Alkoxylation of Difluoroenol Silyl Ethers ; day:06 ; month:08 ; year:2024 ; extent:6
Advanced synthesis & catalysis ; (06.08.2024) (gesamt 6)
- Creator
- DOI
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10.1002/adsc.202400510
- URN
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urn:nbn:de:101:1-2408071419148.065351184485
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:47 AM CEST
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Paut, Julien
- Baldon, Simone
- Anselmi, Elsa
- Dell'Amico, Luca
- Dagousset, Guillaume
- Magnier, Emmanuel
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Intermolecular energy scales based on aromatic ethers and alcohols
Remote Fluorination of α,β‐Unsaturated Carbonyls via Silyl Dienol Ethers
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Lipase‐Mediated Conversion of Protecting Group Silyl Ethers: An Unspecific Side Reaction
Lipase-Mediated Conversion of Protecting Group Silyl Ethers : An Unspecific Side Reaction
Gold-catalyzed alkylation of silyl enol ethers with ortho-alkynylbenzoic acid esters
Fluorination of silyl prosthetic groups by fluorine mediated silyl ether linker cleavage: a concept study with conditions applicable in radiofluorination
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Copper-Catalyzed Difluoroalkylation of Silyl-Enol Ethers
Photoredox-catalyzed silyldifluoromethylation of silyl enol ethers
FLP‐Catalyzed Transfer Hydrogenation of Silyl Enol Ethers
FLP‐Catalyzed Transfer Hydrogenation of Silyl Enol Ethers
Intermolecular energy scales based on aromatic ethers and alcohols
Remote Fluorination of α,β‐Unsaturated Carbonyls via Silyl Dienol Ethers
Ketoester-Ene Reaction of Silyl Enol Ether to Construct Quaternary Carbons
Lipase‐Mediated Conversion of Protecting Group Silyl Ethers: An Unspecific Side Reaction
Lipase-Mediated Conversion of Protecting Group Silyl Ethers : An Unspecific Side Reaction
Gold-catalyzed alkylation of silyl enol ethers with ortho-alkynylbenzoic acid esters