Synthesis, characterization and enzymatic degradation of copolymers of ε-caprolactone and hydroxy-fatty acids
Abstract: New copolymers of ε-caprolactone with three hydroxy-fatty acids, 12-hydroxy stearic acid, 16-hydroxyhexadecanoic acid and ricinoleic acid, were synthesized by catalytic polyesterification. The reactions were carried out in solvent-free systems and in organic solvents as well, using tin (II) 2-ethylhexanoate as catalyst, at different temperatures and molar ratios of the comonomers. Cyclic and linear polymeric products with medium molar weight of about 2000 Da have been synthesized and their chemical structures were confirmed by FT-IR, NMR and MALDI-TOF MS analysis. The synthesis parameters were optimized and the ε-caprolactone/hydroxy acid molar ratio was set as 5:1, according to mass spectrometry results. The biodegradability of the newly synthesized polymers was studied in the presence of Candida antarctica B lipase in phosphate buffer solutions (pH=7.4), at 37°C. The weight-loss profile emphasized the degradation of the 16-hydroxyhexadecanoic acid based polymer samples at more than 50% of their initial weight in 18 days of incubation in the presence of the lipase. The composition of the degradation products was assessed using the GC-MS technique and displayed residues of the comonomers moieties.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Synthesis, characterization and enzymatic degradation of copolymers of ε-caprolactone and hydroxy-fatty acids ; volume:88 ; number:12 ; year:2016 ; pages:1191-1201 ; extent:11
Pure and applied chemistry ; 88, Heft 12 (2016), 1191-1201 (gesamt 11)
- Creator
-
Aparaschivei, Diana
Todea, Anamaria
Păuşescu, Iulia
Badea, Valentin
Medeleanu, Mihai
Şişu, Eugen
Puiu, Maria
Chiriţă-Emandi, Adela
Peter, Francisc
- DOI
-
10.1515/pac-2016-0920
- URN
-
urn:nbn:de:101:1-2024030513454371077597
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
14.08.2025, 10:55 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Aparaschivei, Diana
- Todea, Anamaria
- Păuşescu, Iulia
- Badea, Valentin
- Medeleanu, Mihai
- Şişu, Eugen
- Puiu, Maria
- Chiriţă-Emandi, Adela
- Peter, Francisc
Other Objects (12)
Enzymatic Synthesis of Functional PEGylated Adipate Copolymers
Synthesis, characterization, and crystallization of biodegradable poly (ε-caprolactone)-poly (L-lactide) diblock copolymers
Lipids, fatty acids and hydroxy-fatty acids of Euphausia pacifica
Effects of Grafting Maleic Anhydride onto Poly‐ ε ‐caprolactone on Facilitative Enzymatic Hydrolysis
Enzymatic production of sugar fatty acid esters
Light‐Driven Enzymatic Decarboxylation of Fatty Acids
Enzymatic production of sugar fatty acid esters
Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
Enzymatic synthesis of amino sugar fatty acid esters
Enzymatic synthesis of kraft lignin-acrylate copolymers using an alkaline tolerant laccase
A dataset of branched fatty acid esters of hydroxy fatty acids diversity in foods
Enzymatic Synthesis of Functional PEGylated Adipate Copolymers
Synthesis, characterization, and crystallization of biodegradable poly (ε-caprolactone)-poly (L-lactide) diblock copolymers
Lipids, fatty acids and hydroxy-fatty acids of Euphausia pacifica
Effects of Grafting Maleic Anhydride onto Poly‐ ε ‐caprolactone on Facilitative Enzymatic Hydrolysis
Enzymatic production of sugar fatty acid esters
Light‐Driven Enzymatic Decarboxylation of Fatty Acids
Enzymatic production of sugar fatty acid esters
Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
Enzymatic synthesis of amino sugar fatty acid esters
Enzymatic synthesis of kraft lignin-acrylate copolymers using an alkaline tolerant laccase
A dataset of branched fatty acid esters of hydroxy fatty acids diversity in foods
Enzymatic Synthesis of Functional PEGylated Adipate Copolymers
Synthesis, characterization, and crystallization of biodegradable poly (ε-caprolactone)-poly (L-lactide) diblock copolymers
Lipids, fatty acids and hydroxy-fatty acids of Euphausia pacifica
Effects of Grafting Maleic Anhydride onto Poly‐ ε ‐caprolactone on Facilitative Enzymatic Hydrolysis
Enzymatic production of sugar fatty acid esters
Light‐Driven Enzymatic Decarboxylation of Fatty Acids
Enzymatic production of sugar fatty acid esters
Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
Enzymatic synthesis of amino sugar fatty acid esters
Enzymatic synthesis of kraft lignin-acrylate copolymers using an alkaline tolerant laccase