Successful management of recalcitrant fungal keratitis with topical caspofungin

Abstract: Objective: To report a case of recalcitrant fungal keratitis successfully managed with topical caspofungin acetate in North India.Methods: Case report and literature review.Results: An 18-year-old male patient presented with complaints of redness, watering, pain and diminution of vision in the right eye and was referred to our centre as a case of corneal ulcer. The patient was examined and found to have a near total epithelial defect, with corneal infiltrates approximately 8x8 mm. A provisional diagnosis of polymicrobial keratitis was made based on corneal scraping suggestive of S tap hylococcus aureus and confocal scan revealing fungal hyphae. The patient failed to respond to topical voriconazole 1%, natamycin 5% and moxifloxacin hydrochloride 0.5% with oral voriconazole. In view of the poor response to these drugs, the patient was subsequently administered topical caspofungin 0.5% in place of natamycin and continued on topical and oral voriconazole, in addition to topical mo...

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Successful management of recalcitrant fungal keratitis with topical caspofungin ; volume:12 ; day:18 ; month:07 ; year:2022 ; GMS ophthalmology cases ; 12 (18.07.2022)

Classification and Topics

• Classification: Medizin, Gesundheit

Contributors, Places and Time

• Creator: Goel, Siddhi ; Sharma, Arpit ; Sinha, Rajesh

Further information

• DOI: 10.3205/oc000206
• URN: urn:nbn:de:0183-oc0002060
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:29 AM CEST