Intra-arterial tirofiban in a male nonagenarian with acute ischemic stroke: A case report

Abstract: Nonagenarians with acute ischemic stroke tend to have a higher mortality and morbidity than younger patients. Tirofiban is a glycoprotein IIb/IIIa antagonist that has a therapeutic potential for ischemic stroke. Here, we provide a case report of a 93-year-old male patient with acute ischemic stroke. He presented with right-sided hemiparesis for 2 hours (National Institute of Health Stroke Scale, NIHSS = 23). Immediate treatment with endovascular tirofiban infusion achieved an improvement of intracranial blood flow and a progressively decreased NIHSS one day after admission (NIHSS = 16) and then seven days after admission (NIHSS = 7). After a follow-up of 90 days, the modified ranking score was 2. This case report suggests that endovascular application with tirofiban may be a favorable option for treating nonagenarians presenting with acute ischemic stroke and warrants further study.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Intra-arterial tirofiban in a male nonagenarian with acute ischemic stroke: A case report ; volume:14 ; number:1 ; year:2019 ; pages:515-518 ; extent:4
Open life sciences ; 14, Heft 1 (2019), 515-518 (gesamt 4)

Creator
Ding, Xianhui
Gu, Ao
Yang, Qian
Zhou, Zhiming
Shi, Xiaolei

DOI
10.1515/biol-2019-0057
URN
urn:nbn:de:101:1-2409201716142.972909366983
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:32 AM CEST

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Associated

  • Ding, Xianhui
  • Gu, Ao
  • Yang, Qian
  • Zhou, Zhiming
  • Shi, Xiaolei

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