Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries

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Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: 1 Online-Ressource.

Language: Englisch

Bibliographic citation: Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries ; volume:15 ; number:1 ; day:7 ; month:6 ; year:2024 ; pages:1-11 ; date:12.2024
Nature Communications ; 15, Heft 1 (7.6.2024), 1-11, 12.2024

Creator: Misek, Sean A.
Fultineer, Aaron
Kalfon, Jeremie
Noorbakhsh, Javad
Boyle, Isabella
Roy, Priyanka
Dempster, Joshua
Petronio, Lia
Huang, Katherine
Saadat, Alham
Green, Thomas
Brown, Adam
Doench, John G.
Root, David E.
McFarland, James M.
Beroukhim, Rameen
Boehm, Jesse S.

Contributor: SpringerLink (Online service)

DOI: 10.1038/s41467-024-48957-z

URN: urn:nbn:de:101:1-2408151247123.507916231644

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:48 AM CEST

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Associated

Misek, Sean A.
Fultineer, Aaron
Kalfon, Jeremie
Noorbakhsh, Javad
Boyle, Isabella
Roy, Priyanka
Dempster, Joshua
Petronio, Lia
Huang, Katherine
Saadat, Alham
Green, Thomas
Brown, Adam
Doench, John G.
Root, David E.
McFarland, James M.
Beroukhim, Rameen
Boehm, Jesse S.
SpringerLink (Online service)

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Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG

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Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries

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Other Objects (12)

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males

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FALSE

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Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG

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Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG

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A method to reduce ancestry related germline false positives in tumor only somatic variant calling

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