An environmentally friendly acylation reaction of 2-methylnaphthalene in solvent-free condition in a micro-channel reactor

Abstract: An efficient and solvent-free acylation of 2-methylnaphthalene (2-MN) is presented using acid chloride as both the acylating agent and solvent in a micro channel reactor. The effect of the catalyst, reactant ratio, mixing temperature, reaction temperature and reaction time on the product yield and selectivity was investigated. At room temperature with a reaction time of only 15 min, the target product, 2-methyl-6-propionylnaphthalene (2,6-MPN), was obtained in 72.3% yield with 73.8% selectivity, and 2-methyl-6-acetylnaphthalene (2,6-MAN) was obtained in 54.1% yield with 55.4% selectivity. The route of synthesis provides a more environmentally friendly and efficient method to prepare 2,6-MPN with no other toxic solvents and efficient mass transfer and heat transfer.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: An environmentally friendly acylation reaction of 2-methylnaphthalene in solvent-free condition in a micro-channel reactor ; volume:8 ; number:1 ; year:2019 ; pages:474-479 ; extent:6 ; Green processing & synthesis ; 8, Heft 1 (2019), 474-479 (gesamt 6)

Contributors, Places and Time

• Creator: Li, Wenpeng ; Jin, Haibo ; Yang, Suohe ; Guo, Xiaoyan ; He, Guangxiang ; Zhang, Rongyue

Further information

• DOI: 10.1515/gps-2019-0015
• URN: urn:nbn:de:101:1-2501120422053.635069434821
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:27 AM CEST