Hybridizing Simulated Moving Bed and Electrodialysis: Product Purification and Eluent Regeneration

Abstract: Complex streams in bio‐based industries require efficient downstream processing units. Simulated moving‐bed (SMB) chromatography is known to improve process efficiency by reducing resin and buffer requirement, but it can be further enhanced by technology hybridization. In the current experiments, an SMB system has been integrated with a bipolar electrodialysis (BPED) system. SMB purified γ‐aminobutyric acid (GABA) from a clarified fermentation broth while BPED processed the product‐containing eluent stream into recyclable eluent and purified product streams. The continuous operation did not result in any impurity accumulation.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Hybridizing Simulated Moving Bed and Electrodialysis: Product Purification and Eluent Regeneration ; volume:41 ; number:12 ; year:2018 ; pages:2418-2426 ; extent:9
Chemical engineering & technology ; 41, Heft 12 (2018), 2418-2426 (gesamt 9)

Creator
Kochendoerfer, Kiara
Sa Gomes, Pedro
Rütze, Dennis N.
Pathapati, Trinath
de Wit, Pieter
Zaalberg, Menne

DOI
10.1002/ceat.201800298
URN
urn:nbn:de:101:1-2022090109470677380582
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:25 AM CEST

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Associated

  • Kochendoerfer, Kiara
  • Sa Gomes, Pedro
  • Rütze, Dennis N.
  • Pathapati, Trinath
  • de Wit, Pieter
  • Zaalberg, Menne

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