Longitudinal cardiac dimensions in patients undergoing LVAD implantation
Abstract: Background
In conventional left ventricular assist devices (LVAD), a separate outflow graft is sutured to the ascending aorta. Novel device designs may include a transventricular outflow cannula crossing the aortic valve (AV). While transversal ventricular dimensions are well investigated in patients with severe heart failure, little is known about the longitudinal dimensions. These dimensions are, however, particularly critical for the design and development of mechanical circulatory support (MCS) devices with transaortic outflow cannula.
Methods
In an explorative retrospective cohort study at the University Medical Center Freiburg, Germany, the longitudinal cardiac dimensions of patients undergoing computed tomography angiography (CTA) before and, if available, after LVAD implantation were analyzed. Among others, the following dimensions were assessed: (a) apex to AV, (b) apex to mitral valve, (c) AV to sinotubular junction (STJ), (d) apex to STJ, (e) apex to brachiocephalic artery (BCA), and (f) AV to BCA.
Results
In total, 44 LVAD patients (36 male, age 55.8 years, height 1.75 m) were included. The longitudinal cardiac dimensions were (a) 114.5 ± 12.1 mm, (b) 108.0 ± 12.4 mm, (c) 20.9 ± 2.9, (d) 135.4 ± 13.4 mm, (e) 206.0 ± 18.3, and (f) 91.5 ± 9.8 mm. Postoperatively, (a) and (b) decreased by 31.5% and 39.5%, respectively (N = 14).
Conclusions
Longitudinal cardiac dimensions may be reduced by up to 40% after LVAD implantation. A better knowledge of these dimensions and their postoperative alterations in LVAD patients may improve surgical planning and help to design MCS devices with transventricular outflow cannula
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Anmerkungen
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Artificial organs. - 48, 5 (2024) , 550-558, ISSN: 1525-1594
- Klassifikation
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Medizin, Gesundheit
- Ereignis
-
Veröffentlichung
- (wo)
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Freiburg
- (wer)
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Universität
- (wann)
-
2024
- Urheber
-
Meißner, Florian Gregor
Szvetics, Sophie
Costa Galbas, Michelle
Russe, Maximilian Frederik
Schibilsky, David
Kaier, Klaus
Czerny, Martin
Bothe, Wolfgang
- DOI
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10.1111/aor.14728
- URN
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urn:nbn:de:bsz:25-freidok-2457556
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
25.03.2025, 13:46 MEZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Meißner, Florian Gregor
- Szvetics, Sophie
- Costa Galbas, Michelle
- Russe, Maximilian Frederik
- Schibilsky, David
- Kaier, Klaus
- Czerny, Martin
- Bothe, Wolfgang
- Universität
Entstanden
- 2024
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