Miniaturized Chemical Tags for Optical Imaging
Abstract: Recent advances in optical bioimaging have prompted the need for minimal chemical reporters that can retain the molecular recognition properties and activity profiles of biomolecules. As a result, several methodologies to reduce the size of fluorescent and Raman labels to a few atoms (e.g., single aryl fluorophores, Raman‐active triple bonds and isotopes) and embed them into building blocks (e.g., amino acids, nucleobases, sugars) to construct native‐like supramolecular structures have been described. The integration of small optical reporters into biomolecules has also led to smart molecular entities that were previously inaccessible in an expedite manner. In this article, we review recent chemical approaches to synthesize miniaturized optical tags as well as some of their multiple applications in biological imaging.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Miniaturized Chemical Tags for Optical Imaging ; day:21 ; month:07 ; year:2022 ; extent:1
Angewandte Chemie ; (21.07.2022) (gesamt 1)
- Creator
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Benson, Sam
de Moliner, Fabio
Tipping, William
Vendrell, Marc
- DOI
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10.1002/ange.202204788
- URN
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urn:nbn:de:101:1-2022072215192197828407
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:28 AM CEST
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Associated
- Benson, Sam
- de Moliner, Fabio
- Tipping, William
- Vendrell, Marc
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