Quantitative Formation of Monomeric G‐Quadruplex DNA from Multimeric Structures of c‐Myc Promoter Sequence
Abstract: G‐Quadruplex (G4)‐forming DNA sequences have a tendency to form stable multimeric structures. This can be problematic for studies with synthetic oligodeoxynucleotides. Herein, we describe a method that quantitatively converts multimeric intermolecular structures of the Pu27 sequence from the c‐myc promoter into the desired monomeric G4 by alkaline treatment and refolding.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Quantitative Formation of Monomeric G‐Quadruplex DNA from Multimeric Structures of c‐Myc Promoter Sequence ; volume:21 ; number:17 ; year:2020 ; pages:2445-2448 ; extent:4
ChemBioChem ; 21, Heft 17 (2020), 2445-2448 (gesamt 4)
- Urheber
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Rauser, Valerie
Weinhold, Elmar
- DOI
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10.1002/cbic.202000159
- URN
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urn:nbn:de:101:1-2022061905231747418595
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:36 MESZ
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Beteiligte
- Rauser, Valerie
- Weinhold, Elmar
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