Peptide-based vectors: recent developments
Abstract: Peptides and peptide-cargo complexes have been used for drug delivery and gene therapy. One of the most used delivery vectors are cell-penetrating peptides, due to their ability to be taken up by a variety of cell types and deliver a large variety of cargoes through the cell membrane with low cytotoxicity. In vitro and in vivo studies have shown their possibility and full effectiveness to deliver oligonucleotides, plasmid DNA, small interfering RNAs, antibodies, and drugs. We report in this review some of the latest strategies for peptide-mediated delivery of nucleic acids. It focuses on peptide-based vectors for therapeutic molecules and on nucleic acid delivery. In addition, we discuss recent applications and clinical trials.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Peptide-based vectors: recent developments ; volume:5 ; number:6 ; year:2014 ; pages:479-488 ; extent:10
Biomolecular concepts ; 5, Heft 6 (2014), 479-488 (gesamt 10)
- Urheber
- DOI
-
10.1515/bmc-2014-0024
- URN
-
urn:nbn:de:101:1-2409241626145.248526596509
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:30 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Cerrato, Carmine Pasquale
- Lehto, Tõnis
- Langel, Ülo
Ähnliche Objekte (12)
Peptide-based materials
Recent advances of CREKA peptide-based nanoplatforms in biomedical applications
Peptide‐Based Assemblies for Supercapacitor Applications
Adjuvants for peptide-based cancer vaccines
Peptide-based coatings for flexible implantable neural interfaces
Peptide‐Based Coacervate‐Core Vesicles with Semipermeable Membranes
Towards synthetic cells using peptide-based reaction compartments
Biocatalytic self-assembly of 2D peptide-based nanostructures
Selected peptide-based fluorescent probes for biological applications
The P42 peptide and Peptide-based therapies for Huntington’s disease
Molecular mechanisms and peptide-based modulators of protein aggregation
Development of peptide-based carriers for electronic waste recycling
Peptide-based materials
Recent advances of CREKA peptide-based nanoplatforms in biomedical applications
Peptide‐Based Assemblies for Supercapacitor Applications
Adjuvants for peptide-based cancer vaccines
Peptide-based coatings for flexible implantable neural interfaces
Peptide‐Based Coacervate‐Core Vesicles with Semipermeable Membranes
Towards synthetic cells using peptide-based reaction compartments
Biocatalytic self-assembly of 2D peptide-based nanostructures
Selected peptide-based fluorescent probes for biological applications
The P42 peptide and Peptide-based therapies for Huntington’s disease
Molecular mechanisms and peptide-based modulators of protein aggregation
Development of peptide-based carriers for electronic waste recycling
Peptide-based materials
Recent advances of CREKA peptide-based nanoplatforms in biomedical applications
Peptide‐Based Assemblies for Supercapacitor Applications
Adjuvants for peptide-based cancer vaccines
Peptide-based coatings for flexible implantable neural interfaces
Peptide‐Based Coacervate‐Core Vesicles with Semipermeable Membranes
Towards synthetic cells using peptide-based reaction compartments
Biocatalytic self-assembly of 2D peptide-based nanostructures
Selected peptide-based fluorescent probes for biological applications
The P42 peptide and Peptide-based therapies for Huntington’s disease
Molecular mechanisms and peptide-based modulators of protein aggregation